2005—2024年建德市人间布鲁氏菌病流行特征分析  

Epidemiological characteristics of human brucellosis in Jiande City from 2005 to 2024

作　　者：杨献青[1] 方利洪[1] 方莲 钟荣万[1] 王飞[1] 梁杰[1] 黄雁寅 徐校平[2] YANG Xianqing;FANG Lihong;FANG Lian;ZHONG Rongwan;WANG Fei;LIANG Jie;HUANG Yanyin;XU Xiaoping(Jiande Center for Disease Control and Prevention,Jiande,Zhejiang 311600,China;Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou,Zhejiang 310051,China)

机构地区：[1]建德市疾病预防控制中心,浙江建德311600 [2]浙江省疾病预防控制中心,浙江杭州310051

出　　处：《预防医学》2025年第3期304-306,311,共4页China Preventive Medicine Journal

摘　　要：目的了解2005—2024年浙江省建德市人间布鲁氏菌病(布病)流行特征,为加强布病防控工作提供依据。方法通过中国疾病预防控制信息系统、建德市疾病预防控制中心布病监测年报表和年度布病防治工作总结收集2005—2024年建德市布病病例资料和布病监测资料,采用描述性流行病学方法分析人间布病的流行特征。结果2005—2024年建德市累计监测1125人,血清学阳性18例,阳性率为1.60%;2015—2024年年均血清学阳性率为3.35%,高于2005—2014年的0.57%(P<0.05)。布病确诊病例10例,隐性感染者8例,无死亡病例。发病高峰为3—8月。建德市16个乡镇(街道)中8个有布病病例。男性14例,女性4例,男女比为3.5∶1;年龄40~60岁13例。职业人群16例,均因手直接接触牛羊的流产物、排泄物和畜产品而感染。传染源主要为羊,其次为牛。分离培养5株布鲁氏菌,均为羊种3型菌。结论2005—2024年建德市人间布病疫情总体处于散发低流行水平,2015—2024年有增长趋势,40~60岁男性职业人群是布病防控的重点人群,羊是主要传染源。s:Objective To investigate the epidemiological characteristics of human brucellosis in Jiande City,Zhejiang Province from 2005 to 2024,so as to provide the evidence for strengthening the prevention and control of brucellosis.Methods Data on brucellosis cases and surveillance in Jiande City from 2005 to 2024 were collected through the Chinese Disease Prevention and Control Information System,the annual brucellosis surveillance reports from the Jiande Center for Disease Control and Prevention,and the annual summaries of brucellosis prevention and control efforts.The epidemiological characteristics of human brucellosis were analyzed using a descriptive epidemiological method.Results A total of 1125 individuals were monitored in Jiande City from 2005 to 2024,with 18 seropositive cases identified and the seropositivity rate of 1.60%.The average annual seropositivity rate from 2015 to 2024 was 3.35%,which was significantly higher than that of 0.57% from 2005 to 2014(P<0.05).There were 10 confirmed brucellosis cases and 8 asymptomatic infections,with no reported deaths.The peak incidence occurred between March and August.Among the 16 towns(streets)in Jiande City,8 reported brucellosis cases.Of the brucellosis cases,14 were male and 4 were female,with a male-to-female ratio of 3.5∶1.The majority of cases(13 cases)were aged between 40 and 60 years.Occupational exposure was identified in 16 cases,all of whom were infected through direct hand contact with the excreta,secretions,or animal products of infected sheep or cattle.The primary source of infection was sheep,followed by cattle.Five strains of Brucella were isolated and cultured,all identified as Brucella melitensis biovar 3.Conclusions The brucellosis epidemic in Jiande City remained at a sporadic and low prevalence level from 2005 to 2024,with an increasing trend observed from 2015 to 2024.Male occupational groups aged 40 to 60 years were the key population for brucellosis prevention and control,and sheep were the primary source of infection.

关 键 词：布鲁氏菌病 职业人群 流行特征 

分 类 号：R516.7[医药卫生—内科学]