噻吩并[3,2-d]嘧啶母核探针分子合成及其荧光性质  

Synthesis and fluorescence properties of thiopheno[3,2-d]pyrimidine nucleus probe molecules

作　　者：陈太杰 赵旭飞 燕宇航 CHEN Taijie;ZHAO Xufei;YAN Yuhang(School of Chemistry and Chemical Engineering,Anqing Normal University,Anqing 24601l,China)

机构地区：[1]安庆师范大学化学化工学院,安徽安庆246011

出　　处：《延边大学学报(自然科学版)》2025年第1期37-43,共7页Journal of Yanbian University(Natural Science Edition)

基　　金：安徽省先进催化与能源材料重点实验室开放基金(ZD2023004).

摘　　要：以2-氯-7-碘噻吩并[3,2-d]嘧啶为起始原料,通过Heck偶联和Suzuki偶联等反应合成了一种荧光探针分子DTP-VBT.利用核磁共振(NMR)谱、质谱(MS)对DTP-VBT的结构进行了表征,利用紫外吸收光谱(UV)、红外光谱(IR)对DTP-VBT的光学性质进行了测试和分析.实验结果显示,DTP-VBT对氯氧根离子(ClO^(-))具有优异的特异性识别能力,其识别机理为ClO^(-)对硼酸频哪醇酯基团的特异性氧化而使得探针分子结构发生变化.研究结果可为开发新型荧光探针提供良好参考。A fluorescent probe molecule DTP-VBT was synthesized from 2-chloro-7-iodothieno[3,2-d]pyrimidine as the starting material through Heck coupling and Suzuki coupling reactions.The structure of the new compound was thoroughly characterized using nuclear magnetic resonance(NMR),mass spectrometry(MS).The optical properties of DTP-VBT were tested and analyzed using ultraviolet spectrum(UV)and infrared absorption spectrometry(IR).The experimental outcomes demonstrated that this probe molecule possesses excellent specific recognition capability for hypochlorite ions(ClO^(-)).The recognition mechanism is that hypochlorite ions specifically oxidize the pinacol boronate ester group,thereby causing changes in the structure of the probe molecule.The research results can provide a good reference for the development of new fluorescent probes.

关 键 词：噻吩并[3 2-d]嘧啶 次氯酸根 荧光探针 荧光性质 环境黏度 

分 类 号：O644.19[理学—物理化学]