土茯苓化学成分及药理作用研究进展  

Research progress on chemical constituents and pharmacological properties of Smilacis Glabrae Rhizoma

作　　者：刘苏杰 阮佳鑫 王晨 王晓凡 闫嘉鹤 王宇[2] 刘树民[2] LIU Sujie;RUAN Jiaxin;WANG Chen;WANG Xiaofan;YAN Jiahe;WANG Yu;LIU Shumin(Graduate School,Heilongjiang University of Chinese Medicine,Harbin 150040,China;Institute of Traditional Chinese Medicine,Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学研究生院,黑龙江哈尔滨150040 [2]黑龙江中医药大学中医药研究院,黑龙江哈尔滨150040

出　　处：《中草药》2025年第3期1064-1077,共14页Chinese Traditional and Herbal Drugs

基　　金：国家重点研发计划“中医药现代化”重点专项2022年度项目(2022YFC3502103-04)。

摘　　要：土茯苓Smilacis Glabrae Rhizoma为百合科植物光叶菝葜的干燥根状茎,具有解毒除湿、通利关节的功效。主要用于治疗银屑病、痛风、慢性肾炎等疾病。研究表明,土茯苓的活性成分主要包括黄酮类、苯丙素类、甾体类、有机酸类、挥发油类等。大量研究证实土茯苓具有抗炎、免疫调节、抗氧化、抗肿瘤等药理作用。通过对近年来国内外关于土茯苓化学成分和药理作用研究报道进行总结,为土茯苓的开发利用提供理论基础,以期获得更好的实用价值。Tufuling(Smilacis Glabrae Rhizoma)is the desiccated underground stem of the plant Smilax glabra,belonging to Liliaceae family.It possesses the properties of detoxifying,dehumidification,and improvement of joint health,which is primarily employed in the treatment of psoriasis,gout,chronic nephritis and etc.Studies have demonstrated that the primary active constituents of Smilacis Glabrae Rhizoma are flavonoids,phenylpropanoids,steroids,organic acids,volatile oils,and other compounds.Multiple investigations have verified that Smilacis Glabrae Rhizoma exhibits diverse pharmacological properties,including anti-inflammatory,immune-modulating,antioxidant and antitumor activities.By summarizing the research reports on the chemical composition and pharmacological effects of Smilacis Glabrae Rhizoma at home and abroad in recent years,a theoretical basis is provided for the development and utilization of Smilacis Glabrae Rhizoma,in order to obtain better practical value.

关 键 词：土茯苓 文献计量学 网络药理学 抗痛风 抗炎 免疫调节 落新妇苷 新落新妇苷 

分 类 号：R285[医药卫生—中药学]