早筛 早诊 早治,阻止乙型肝炎病毒感染相关不良临床结局  

Early screening,early diagnosis and early treatment can prevent adverse clinical outcomes related to HBV infection

作　　者：丁洋[1] 窦晓光[1] DING Yang;DOU Xiao-guang(Department of Infectious Diseases,Shengjing Hospital of China Medical University,Shenyang 110022,China)

机构地区：[1]中国医科大学附属盛京医院感染科,辽宁沈阳110022

出　　处：《中国实用内科杂志》2025年第2期89-91,95,共4页Chinese Journal of Practical Internal Medicine

基　　金：辽宁省科技厅应用基础研究计划(No.2022JH2/101500009)。

摘　　要：慢性乙型肝炎病毒(HBV)感染者如果没有得到及时有效的抗病毒治疗,最终会因为肝衰竭、肝硬化失代偿、肝细胞癌而导致死亡。虽然目前抗毒治疗不能彻底治愈疾病,但早筛、早诊和早治可阻止或延缓其进展为相关终末期肝病。HBV普遍筛查联合乙肝疫苗接种,是实现世界卫生组织提出的2030年消除病毒性肝炎公共卫生危害的关键措施。针对筛查后发现的HBV感染者,临床管理也至关重要,早期诊断和及时抗病毒治疗是阻止HBV不良临床结局最有效的措施。The patients with chronic hepatitis B virus(HBV)infection will eventually die due to liver failure,decompensated cirrhosis,and hepatocellular carcinoma without timely and effective antiviral treatment.Although current antiviral therapies cannot completely cure the disease,early screening,early diagnosis and early treatment can prevent or delay its progression to related end-stage liver disease.Comprehensive screening of HBV combined with hepatitis B vaccination is the key measures to achieve the World Health Organization's proposal of eliminating the public health threat of viral hepatitis by 2030.Clinical management of HBV infection after screening is also critical,and early diagnosis and timely antiviral therapy are the most effective measures to prevent adverse clinical outcomes related to HBV infection.

关 键 词：乙型肝炎 慢性 筛查 诊断 抗病毒治疗 

分 类 号：R512.6[医药卫生—内科学]