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作 者:黎海莹 许文伟[2] 田波 刘志琴 陈玉华 Li Haiying;Xu Wenwei;Tian Bo;Liu Zhiqin;Chen Yuhua(The First College of Clinical Medicine,Guangdong Medical University,Zhanjiang 524001,China;Department of Endocrinology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Department of Endocrinology,Affiliated Longgang District People′s Hospital of Guangdong Medical University,Shenzhen 518172,China)
机构地区:[1]广东医科大学第一临床医学院,湛江524001 [2]南方医科大学南方医院内分泌代谢科,广州510515 [3]广东医科大学深圳市龙岗区人民医院内分泌代谢科,深圳518172
出 处:《国际内分泌代谢杂志》2025年第1期47-50,共4页International Journal of Endocrinology and Metabolism
基 金:深圳市龙岗区科技发展专项资金(LGKCYLWS2021000009)。
摘 要:血糖监测技术的发展尤为迅速,葡萄糖管理指标(GMI)作为血糖监测的一种先进的补充性工具,是预估实验室糖化血红蛋白A1c(HbA1c)的辅助工具。2023年美国糖尿病协会(ADA)指南明确GMI可以作为判断血糖控制的一种参数,建议可将14 d的持续葡萄糖监测(CGM)评估中葡萄糖目标范围内时间(TIR)和GMI作为HbA1c的补充指标。HbA1c对血糖变化的缓慢反应和受红细胞生理变化的影响是HbA1c与CGM衍生指标不一致的原因。在血糖监测方面GMI及HbA1c各有优势,应该将两个指标进行互相结合、互相补充以便更优化调整血糖,全面了解患者血糖的动态变化,对患者的血糖管理具有更大的意义。The development of glucose monitoring technology is particularly rapid.As an advanced supplementary tool of blood glucose monitoring,glucose monitoring indicator(GMI)is an auxiliary tool of estimating laboratory haemoglobin A1c(HbA1c).The 2023 guidelines from the American Diabetes Association(ADA)specify that GMI can be used as a parameter to determine glucose control.It is recommended that TIR and GMI can be used as complementary measures of HbA1c in the 14-day continuous glucose monitoring(CGM).The slow response of HbA1c to changes in blood glucose and the influence of physiological changes in red blood cells are the reasons for the inconsistency between HbA1c and CGM derived indicators.Both GMI and HbA1c have their own advantages.Two indexes should be combined and supplemented to better optimize blood glucose adjustment and comprehensively understand the dynamic changes of blood glucose in patients,which has greater significance for blood glucose management in patients.Therefore,this paper summarizes clinical significance,differences between HbA1c and clinical applications of GMI.
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