电化学传感器用于检测抗寄生虫药物的应用进展  

Recent progress in electrochemical sensors for detecting antiparasitic drugs

作　　者：方涛 AWAIS Ihsan 潘彦冰 GHULAM Murtaza 田瑞庭 程寒[1,2] FANG Tao;AWAIS Ihsan;PAN Yanbing;GHULAM Murtaza;TIAN Ruiting;CHENG Han(South-Central Minzu University,School of Pharmaceutical Sciences,Wuhan 430074,China;South-Central Minzu University,Ethnopharmacology Level 3 Laboratory,National Administration of Traditional Chinese Medicine,Wuhan 430074,China;Department of Biosciences,COMSATS University Islamabad Sahiwal Campus,Sahiwa 40210l,Pakistan;Department of Pharmacy,COMSATS University Islamabad Lahore Campus,Lahore 54000,Pakistan)

机构地区：[1]中南民族大学药学院,武汉430074 [2]中南民族大学国家中医药管理局民族药学三级实验室,武汉430074 [3]伊斯兰堡COMSATS大学生物科技学院,巴基斯坦萨希瓦尔40210 [4]伊斯兰堡COMSATS大学药学院,巴基斯坦拉合尔54000

出　　处：《中南民族大学学报(自然科学版)》2025年第3期343-356,共14页Journal of South-Central Minzu University(Natural Science Edition)

基　　金：科技部外国专家资助项目(DL2023185001L);中南民族大学“中药现代化传承与创新”科研团队(XTZ24025);湖北省科技攻关资助项目(2024EHA054);湖北省“传统医药资源评价与利用国际科技合作基地”(SH2311)。

摘　　要：随着抗寄生虫药物在医学、食品行业、环境卫生等方面的广泛应用,寄生虫的耐药性也随之增加,其中假劣伪制药物是导致寄生虫产生耐药性的重要原因之一.因此,开发灵敏快捷的抗寄生虫药物监测方法至关重要.在各类抗寄生虫药物检测技术中,电化学方法因操作简便,响应时间快,灵敏度高,成本低和仪器便携等优势展示出广阔的应用前景.评述了近年来用于抗寄生虫药物检测的电化学传感器研究进展及其在实际样品分析中的应用,并重点比较了不同复合传感界面及其检测性能.电化学传感器在抗寄生虫药物检测领域在未来的发展趋势是更高的灵敏度、更快的检测速度及更广泛的应用等.With the widespread use of antiparasitic drugs in medicine,food industry,environmental hygiene,and other fields,there has been an increase in parasite resistance.Counterfeit and substandard drugs are significant contributors to the development of this resistance.Therefore,it is crucial to develop sensitive and rapid antiparasitic drug monitoring methods.Compared with various anti-parasitic drug detection methods,electrochemical methods have demonstrated extensive potential due to their advantages of simple operation,fast response time,high sensitivity,low-cost and portable instrument.Herein,the research progress of electrochemical sensors in the detection of anti-parasitic drugs and their application in actual sample analysis in recent years are reviewed.Then,the sensing properties of different composite interfaces are compared.Finally,the future development trend of electrochemical sensors in the field of anti-parasitic drug detection is prospected,including higher sensitivity,faster detection speed and wider application range.

关 键 词：抗寄生虫药物 电化学方法 传感器 电极 

分 类 号：R917[医药卫生—药物分析学]