富血小板血浆联合关节镜下清理术治疗半月板损伤合并膝关节炎患者的效果分析  

Effect Analysis of Platelet-Rich Plasma Combined with Arthroscopic Debridement in the Treatment of Patients with Meniscus Injury and Knee Arthritis

作　　者：胡珂 HU Ke(Department of Articulation No.3,Zhangqiu District Hospital of Traditional Chinese Medicine,Jinan 250000,China)

机构地区：[1]山东省济南市章丘区中医医院关节三科,山东济南250000

出　　处：《中国伤残医学》2024年第24期26-29,共4页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:探讨半月板损伤合并膝关节炎患者应用富血小板血浆(PRP)联合关节镜下清理术的治疗效果。方法:选择2021年1月—2023年12月济南市章丘区中医医院收治102例半月板损伤合并膝关节炎患者为研究对象,按随机数字表法将其分为研究组和对照组,各51例。研究组采用PRP联合关节镜下清理术治疗,对照组采用关节镜下清理术治疗。比较两组临床疗效、血清指标水平及膝关节临床症状与功能。结果:研究组临床治疗总有效率为98.04%,高于对照组的80.39%,差异有统计学意义(P<0.05)。术后3个月,研究组血红蛋白、红细胞沉降率、超敏C反应蛋白、血清P物质水平均低于对照组,转化生长因子-β水平高于对照组,差异均有统计学意义(P<0.05)。术后6个月,研究组西安大略和麦克马斯特大学骨关节炎指数评分低于对照组,Lysholm膝关节评分高于对照组,差异均有统计学意义(P<0.05)。结论:半月板损伤合并膝关节炎患者接受PRP联合关节镜下清理术治疗,可取得良好疗效,有效减轻炎症反应,改善膝关节临床症状与功能,具有一定的临床应用价值。Objective:To investigate the therapeutic effect of platelet-rich plasma(PRP)combined with arthroscopic debridement in patients with meniscus injury and knee arthritis.Methods:A total of 102 patients with meniscus injury combined with knee arthritis treated in Zhangqiu District Hospital of Traditional Chinese Medicine of Jinan City from January 2021 to December 2023 were selected as the study objects,and were divided into a study group and a control group according to random number table method,with 51 cases in each group.The study group was treated with PRP combined with arthroscopic debridement,and the control group was treated with arthroscopic debridement.The clinical effect,serum index level,clinical symptoms and function of knee joint were compared between the two groups.Results:The total effective rate of the study group was 98.04%,which was higher than 80.39%of the control group,the difference was statistically significant(P<0.05).Three months after surgery,the levels of hemoglobin,erythrocyte sedimentation rate,hypersensitive C-reactive protein and serum substance P in the study group were lower than those in the control group,and the levels of transforming growth faction-βwere higher than those in the control group,with statistical significance(P<0.05).Six months after surgery,the osteoarthritis index scores of Western Ontario University and McMaster University in the study group were lower than those of the control group,and the knee joint scores of Lysholm were higher than those of the control group,with statistical significance(P<0.05).Conclusion:PRP combined with arthroscopic debridement for patients with meniscus injury and knee arthritis can achieve good curative effect,effectively reduce inflammatory response,improve clinical symptoms and function of knee joint,and have certain clinical application value.

关 键 词：半月板损伤 膝关节炎 富血小板血浆 关节镜下清理术 治疗效果 功能恢复 

分 类 号：R684.3[医药卫生—骨科学]