腹腔镜引导下胆囊切除术对胆囊结石患者的治疗效果分析  

Analysis of the Therapeutic Effect of Laparoscopic Guided Cholecystectomy on Patients with Gallstones

作　　者：危君庆 邹成玉 WEI Junqing;ZOU Chengyu(Department of General Surgery,Fuzhou Linchuan District Second People’s Hospital,Fuzhou 344000,China)

机构地区：[1]江西省抚州市临川区第二人民医院普外科,江西抚州344000

出　　处：《中国伤残医学》2024年第24期49-52,共4页Chinese Journal of Trauma and Disability Medicine

摘　　要：目的:探讨腹腔镜引导下胆囊切除术(LC)在胆囊结石(GS)患者中的疗效。方法:选取2022年4月—2024年5月抚州市临川区第二人民医院收治的80例GS患者为研究对象,采用随机数字表法将其分为研究组和对照组,各40例。研究组采用LC治疗,对照组采用常规开腹胆囊切除术治疗。比较两组疼痛程度、术后恢复情况、炎症反应指标及并发症发生情况。结果:术后24 h,研究组疼痛视觉模拟评分为(4.42±0.95)分,低于对照组的(5.12±1.04)分,差异有统计学意义(P<0.05)。研究组术后肛门首次排气时间、术后首次排便时间、术后首次下床活动时间及住院时间分别为(1.22±0.28)d、(1.67±0.41)d、(1.62±0.33)d、(5.56±1.06)d,均短于对照组的(1.87±0.34)d、(2.15±0.52)d、(2.78±0.67)d、(7.21±1.12)d,差异均有统计学意义(P<0.05)。术后24 h,研究组白细胞计数、白细胞介素-6、肿瘤坏死因子-α、C反应蛋白水平分别为(8.72±1.53)×109/L、(188.56±23.64)ng/L、(48.21±5.23)mmol/L、(61.65±8.45)mg/L,均低于对照组的(11.33±1.98)×109/L、(223.60±25.71)ng/L、(80.86±8.47)mmol/L、(70.76±10.23)mg/L,差异均有统计学意义(P<0.05)。研究组并发症发生率为5.00%低于对照组的20.00%,差异有统计学意义(P<0.05)。结论:LC应用于GS患者中,可有效减轻患者术后疼痛程度,促进术后恢复,还可减轻炎症反应,一定程度上减少并发症的发生。Objective:To investigate the efficacy of laparoscopic guided cholecystectomy(LC)in patients with gallstones(GS).Methods:A total of 80 patients with GS treated in the Fuzhou Linchuan District Second People’s Hospital from April 2022 to May 2024 were selected as the study objects,and were divided into a study group and a control group with 40 cases in each group by random number table method.The study group was treated with LC,while the control group was treated with routine open cholecystectomy.The pain degree,postoperative recovery,inflammatory response index and complications were compared between the two groups.Results:At 24 h after operation,the Pain Visual Analogue Score of the study group was(4.42±0.95),which was lower than(5.12±1.04)of the control group,the difference was statistically significant(P<0.05).In the study group,the first postoperative anal exhaust time,the first postoperative defecation time,the first postoperative movement time and the length of hospital stay were(1.22±0.28)d,(1.67±0.41)d,(1.62±0.33)d and(5.56±1.06)d,respectively,which were shorter than(1.87±0.34)d,(2.15±0.52)d,(2.78±0.67)d and(7.21±1.12)d in the control group,the differences were statistically significant(P<0.05).At 24 h after operation,leukocyte count,interleukin-6,tumor necrosis factor-αand C-reactive protein levels in the study group were(8.72±1.53)×109/L,(188.56±23.64)ng/L,(48.21±5.23)mmol/L,(61.65±8.45)mg/L,respectively,which were lower than(11.33±1.98)×109/L,(223.60±25.71)ng/L,(80.86±8.47)mmol/L,(70.76±10.23)mg/L of the control group,and the differences were statistically significant(P<0.05).The complication rate of the study group was 5.00%,which was lower than 20.00%of the control group,the difference was statistically significant(P<0.05).Conclusion:The application of LC in patients with GS can effectively reduce the degree of postoperative pain,promote postoperative recovery,reduce inflammatory response,and reduce the occurrence of complications to some extent.

关 键 词：胆囊结石 腹腔镜 胆囊切除术 疼痛程度 并发症 术后恢复 

分 类 号：R65[医药卫生—外科学]