冠心病患者同型半胱氨酸水平与中医体质类型相关性的调查分析  

Investigation and analysis of the correlation between homocysteine level and TCM constitution type in patients with coronary heart disease

作　　者：张新贵[1] 王长虹 王进[1] ZHANG Xingui;WANG Changhong;WANG Jin(Nanyang First People's Hospital,Nanyang 473000,China)

机构地区：[1]南阳市第一人民医院,河南南阳473000

出　　处：《临床医学研究与实践》2025年第8期29-32,共4页Clinical Research and Practice

摘　　要：目的调查分析冠心病患者同型半胱氨酸(Hcy)水平与中医体质类型的相关性。方法选取2022年5月至2023年5月住院的144例冠心病患者作为冠心病组,另随机选取同期体检的30例健康人群为对照组。两组均进行Hcy水平测定,并将中医体质类型分为血瘀质型、气虚质型、湿热质型、痰湿质型、阴虚质型、阳虚质型、气郁质型、特秉质型和平和质型;按邪实、虚弱两类体质分类,血瘀质型、痰湿质型、气郁质型及湿热质型为邪实体质,气虚质型、阳虚质型及阴虚质型为虚弱体质。比较冠心病组和对照组、不同中医体质类型冠心病患者、邪实体质与虚弱体质冠心病患者的Hcy水平。结果144例冠心病患者中医体质分型中,以血瘀质型、气虚质型、湿热质型、痰湿质型和阴虚质型占比较高,均高于10%;而阳虚质型、气郁质型、特秉质型和平和质型占比较低,均小于3%。冠心病组患者的Hcy水平显著高于对照组(P<0.05);不同中医体质类型冠心病患者的Hcy水平比较,差异具有统计学意义(P<0.05);血瘀质型患者的Hcy水平最高,痰湿质型、气虚质型、湿热质型、阴虚质型、阳虚质型、平和质型、特秉质型患者的Hcy水平依次降低,气郁质型患者的Hcy水平最低。结论血瘀质型、气虚质型、湿热质型是冠心病患者常见体质类型,可能具有更高的冠心病发病风险,Hcy高表达可作为冠心病预警因子,Hcy水平可作为冠心病中医体质分型的客观化指标。Objective To investigate and analyze the correlation between homocysteine(Hcy)level and TCM constitution type in patients with coronary heart disease.Methods A total of 144 patients with coronary heart disease who were hospitalized from May 2022 to May 2023 were selected as coronary heart disease group,and 30 healthy people who underwent physical examination during the same period were randomly selected as control group.The Hcy level was measured,and the TCM constitution types were divided into blood stasis type,Qi deficiency type,damp heat type,phlegm dampness type,Yin deficiency type,Yang deficiency type,Qi stagnation type,special type and peace type.According to the classification of two types of constitution,blood stasis type,phlegm dampness type,Qi stagnation type and damp heat type were pathogenic excess constitutions,and Qi deficiency type,Yang deficiency type and Yin deficiency type were weak constitution.The Hcy levels of the coronary heart disease group and the control group,coronary heart disease patients with different TCM constitution types,coronary heart disease patients with pathogenic excess constitution and weak constitution were compared.Results Among the 144 patients with coronary heart disease,the proportion of TCM constitution types,including blood stasis type,Qi deficiency type,damp heat type,phlegm dampness type and Yin deficiency type,was higher than 10%;the proportion of Yang deficiency type,Qi stagnation type,special type and peace type was relatively low,all less than 3%.The level of Hcy in the coronary heart disease group was significantly higher than that in the control group(P<0.05),there was a statistically significant difference in Hcy level among patients with coronary heart disease of different TCM constitution types(P<0.05),the Hcy level of patients with blood stasis type was the highest,and the Hcy level of patients with phlegm dampness type,Qi deficiency type,damp heat type,Yin deficiency type,Yang deficiency type,peace type and special type decreased in turn,and the Hcy level

关 键 词：冠心病 同型半胱氨酸 中医体质 

分 类 号：R259[医药卫生—中西医结合]