妊娠期急性脂肪肝并多器官功能障碍综合征诊治一例  

Diagnosis and treatment of acute fatty liver of pregnancy complicated with multiple organ dysfunction syndrome:a case report

作　　者：张芬芬 冯晓萍[2] 张小燕 ZHANG Fen-fen;FENG Xiao-ping;ZHANG Xiao-yan(Maternal and Child Health Hospital of Hubei Province,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430070,Hubei,CHINA;Huangshi Central Hospital/Affiliated Hospital of Hubei Polytechnic University,Huangshi 435000,Hubei,CHINA)

机构地区：[1]华中科技大学同济医学院附属湖北省妇幼保健院,湖北武汉430070 [2]黄石市中心医院/湖北理工学院附属医院,湖北黄石435000

出　　处：《海南医学》2025年第5期724-728,共5页Hainan Medical Journal

摘　　要：妊娠期急性脂肪肝(AFLP)为妊娠末期发生的以肝细胞脂肪浸润、肝衰竭和肝性脑病为特征的疾病,又称产科急性假性黄色肝萎缩,起病急、进展快、母儿病死率高,缺乏早期特异性临床表现,早期识别困难,多学科协助诊疗是确保良好母婴结局的关键。本文报道妊娠期急性脂肪肝并多器官功能障碍综合征一例,以期为同行提供参考。Acute fatty liver of pregnancy(AFLP)is a disease that occurs in late pregnancy and is characterized by fatty infiltration of hepatocytes,liver failure,and hepatic encephalopathy.Also known as acute pseudo-yellow hepatic atrophy in obstetrics,AFLP presents with rapid onset and progression,high maternal and fetal mortality,and a lack of early specific clinical manifestations,making early recognition challenging.Multidisciplinary collaboration in the diagnosis and treatment is crucial for ensuring favorable maternal and neonatal outcomes.This article reports a case of AFLP complicated with multiple organ dysfunction syndrome(MODS)to provide reference for clinicians.

关 键 词：妊娠期急性脂肪肝 多器官功能障碍综合征 早期识别 多学科协助 

分 类 号：R714.25[医药卫生—妇产科学]