火龙罐治疗早中期膝骨关节炎的疗效观察  

Observations on the efficacy of Huolong cupping for early-middle stage knee osteoarthritis

作　　者：苏心哲 程韶[1,2,3] 张北 马金昕 武圣超 王上增 SU Xinzhe;CHENG Shao;ZHANG Bei;MA Jinxin;WU Shengchao;WANG Shangzeng(Henan University of Chinese Medicine,Zhengzhou 450046,China;Henan Province Hospital of Traditional Chinese Medicine(Henan University of Chinese Medicine Second Hospital),Zhengzhou 450002,China;Henan Engineering Research Center,Zhengzhou 450002,China)

机构地区：[1]河南中医药大学,郑州450046 [2]河南省中医院(河南中医药大学第二附属医院),郑州450002 [3]河南省工程研究中心,郑州450002

出　　处：《上海针灸杂志》2025年第3期277-282,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：河南省高校科技创新团队支持计划项目(24IRTSTHN040);河南省中医药科学研究专项课题项目(2023ZYZD06,2021ZY2010,2019ZY2035);河南省自然科学基金项目(222300420486);郑州市科技惠民计划项目。

摘　　要：目的观察火龙罐治疗早中期膝骨关节炎的临床疗效。方法将108例早中期膝骨关节炎患者随机分为对照组和观察组,每组54例。对照组给予塞来昔布胶囊治疗,观察组在对照组基础上给予火龙罐治疗。比较两组治疗前、治疗后、治疗后3个月疼痛视觉模拟量表(visual analog scale,VAS)评分、西安大略和麦克马斯特大学骨关节炎指数(Western Ontario and McMaster University osteoarthritis index,WOMAC)评分、Lysholm膝关节评分量表评分、血清炎症因子[白细胞介素-1β(interlenkin-1β,IL-1β)、白细胞介素-6(interlenkin-6,IL-6)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)]水平以及膝关节伸肌和屈肌峰力矩。结果两组治疗后及治疗后3个月VAS评分较治疗前显著降低,且观察组VAS评分明显低于对照组,差异具有统计学意义(P<0.05)。两组治疗后及治疗后3个月WOMAC评分较治疗前显著降低,Lysholm膝关节评分量表评分较治疗前显著升高,且观察组WOMAC评分和Lysholm膝关节评分量表评分明显优于对照组,差异具有统计学意义(P<0.05)。两组治疗后及治疗后3个月血清IL-1β、IL-6和TNF-α水平较治疗前显著降低,且观察组血清IL-1β、IL-6和TNF-α水平明显低于对照组,差异具有统计学意义(P<0.05)。两组治疗后及治疗后3个月伸肌和屈肌峰力矩较治疗前显著升高,且观察组伸肌和屈肌峰力矩明显高于对照组,差异具有统计学意义(P<0.05)。结论火龙罐治疗早中期膝骨关节炎,可减轻炎症反应,增强膝关节周围肌肌力,缓解患者疼痛,改善膝关节功能。Objective To observe the clinical efficacy of Huolong cupping for early-middle stage knee osteoarthritis.Method One hundred and eight patients with early-middle stage knee osteoarthritis were randomized to control and observation groups,with 54 cases in each group.The control group was treated with celecoxib capsules and the observation group,by Huolong cupping in addition.The pain visual analog scale(VAS)score,the Western Ontario and McMaster University osteoarthritis index(WOMAC)score,the Lysholm Knee Scoring Scale score,serum inflammatory factor[interlenkin-1b(IL-1b),interlenkin-6(IL-6)levels and tumor necrosis factor-a(TNF-a)]and knee extensor and flexor peak torque were compared between the two groups before,after and three months after treatment.Result At the end of treatment and three months after,the VAS score decreased markedly in the two groups compared with before(P<0.05)and was significantly lower in the observation group than in the control group,with a statistically significant difference(P<0.05).At the end of treatment and three months after,the WOMAC score decreased markedly and the Lysholm Knee Scoring Scale score increased markedly in the two groups compared with before,they were significantly better in the observation group than in the control group,with statistically significant differences(P<0.05).At the end of treatment and three months after,serum IL-1b,IL-6 and TNF-alevels decreased markedly in the two groups compared with before and were significantly lower in the observation group than in the control group,with statistically significant differences(P<0.05).At the end of treatment and three months after,extensor and flexor peak torque increased markedly in the two groups compared with before and was significantly higher in the observation group than in the control group,with statistically significant differences(P<0.05).Conclusion Huolong cupping can relieve the pain and improve knee joint function by reducing inflammatory reactions and increasing the force of the muscles around the knee

关 键 词：骨关节炎 膝 拔罐疗法 灸法 火龙罐 膝关节功能 

分 类 号：R246.2[医药卫生—针灸推拿学]