超声引导下甲状腺结节射频消融术与传统开放手术的疗效及安全性对比分析  

Comparative analysis of efficacy and safety of ultrasound-guided radiofrequency ablation and traditional open surgery for thyroid nodules

作　　者：李晶[1] Li Jing(Fu Xing Hospital,Capital Medical University,Beijing 100045,China)

机构地区：[1]首都医科大学附属复兴医院,北京100045

出　　处：《首都食品与医药》2025年第5期42-44,共3页Capital Food Medicine

摘　　要：目的 探究超声引导下甲状腺结节射频消融术与传统开放手术的疗效及安全性.方法 选取本院自2022年8月-2023年2月收治的良性甲状腺结节患者98例,采用随机数表法分成两组,每组各49例,对照组采取传统开放手术治疗,观察组采取超声引导下射频消融术治疗,对比两组临床疗效、甲状腺结节体积缩小率、治疗前后甲状腺激素指标,同时观察并发症情况.结果 观察组与对照组相比,临床总有效率较高,甲状腺结节体积缩小率较高(P<0.05).两组治疗后与治疗前相比,FT3、FT4及TSH水平均较低,但观察组FT3、FT4及TSH水平高于对照组(P<0.05).两组患者的并发症发生率比较,差异无统计学意义(P>0.05).结论 超声引导下甲状腺结节射频消融术与传统开放手术的应用均可获得显著临床疗效,但前者疗效更加突出,尽管两种方法均会对甲状腺激素指标造成影响,但前者造成的影响较小,整体安全性也较高.Objective To investigate and analyze the efficacy and safety of ultrasound-guided radiofrequency ablation(RFA)compared to traditional open surgery for the treatment of benign thyroid nodules.Methods Ninety-eight patients with benign thyroid nodules admitted to our hospital from August 2022 to February 2023 were randomly divided into two groups(n=49 per group)using a random number table.The control group received traditional open surgery,while the observation group underwent ultrasound-guided RFA.The two groups were compared in terms of clinical efficacy,thyroid nodule volume reduction rate,thyroid hormone levels before and after treatment,and the incidence of complications.Results The observation group showed a significantly higher clinical total effective rate and a higher thyroid nodule volume reduction rate compared to the control group(P<0.05).Both groups showed lower FT3,FT4,and TSH levels after treatment compared to pre-treatment levels.However,the observation group exhibited significantly higher post-treatment FT3,FT4,and TSH levels compared to the control group(P<0.05).There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Both ultrasound-guided radiofrequency ablation and traditional open surgery achieve significant clinical efficacy in treating benign thyroid nodules,but RFA demonstrates superior efficacy.While both methods affect thyroid hormone levels,RFA causes a smaller impact.Overall,RFA demonstrates higher safety.

关 键 词：超声引导下射频消融术 传统开放手术 良性甲状腺结节 甲状腺激素指标 安全性 

分 类 号：R581[医药卫生—内分泌]