艾司氯胺酮在儿科围术期应用研究进展  

Progress in the research of ketamine during pediatric perioperative period

作　　者：贾韡 章艳君[1] 刘金柱[1] JIA Wei;ZHANG Yanjun;LIU Jinzhu(Department of Anesthesiology,Tianjin Children's Hospital(Children's Hospital,Tianjin University,Tianjin Key Laboratory of Birth Defects for Prevention and Treatment),Tianjin 300134,China)

机构地区：[1]天津市儿童医院(天津大学儿童医院,天津市儿童出生缺陷防治重点实验室)麻醉科,天津300134

出　　处：《天津药学》2025年第2期254-256,共3页Tianjin Pharmacy

摘　　要：艾司氯胺酮是氯胺酮的右旋异构体,具有强效镇痛、镇静和抗焦虑作用,以及相对较小的呼吸抑制作用,这使得其成为儿科麻醉领域的重要药物。对艾司氯胺酮的药理作用进行阐述,并对艾司氯胺酮在儿科围术期的具体应用、不良反应进行汇总和综述,并对艾司氯胺酮在儿科围术期的应用进行展望,旨在为儿科医生提供参考。Esketamine is the right-handed isomer of ketamine,which has potent analgesic,sedative,and anti-anxiety effects,as well as relatively small respiratory inhibitory effects,making it an important drug in the field of pediatric anesthesia.This article elaborated on the pharmacological effects of ketamine,summarized and reviewed the specific applications and adverse reactions of ketamine in pediatric perioperative period,and finally looked forward to the application of ketamine in pediatric perioperative period,aiming to provide reference for pediatricians.

关 键 词：艾司氯胺酮 儿科 围术期 应用进展 

分 类 号：R971.2[医药卫生—药品]