系统性红斑狼疮患者运动干预的最佳证据总结  

Summary of best evidence for exercise interventions in patients with systemic lupus erythematosus

作　　者：史君伟 蔡德慧 王鑫浩 郑金龙 康薇 徐炜[4] Shi Junwei;Cai Dehui;Wang Xinhao;Zheng Jinlong;Kang Wei;Xu Wei(Wuxi Medical College of Jiangnan University,Wuxi 214122,China;Department of Rheumatology and Immunology,Minda Hospital of Hubei Minzu University,Enshi 445000,China;Department of Emergency Medicine,Xiangyang Central Hospital,Xiangyang 441100,China;Department of Orthopedics,Tongren Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200336,China)

机构地区：[1]江南大学无锡医学院,无锡214122 [2]湖北民族大学附属民大医院风湿免疫科,恩施445000 [3]襄阳市中心医院急诊科,襄阳441100 [4]上海交通大学医学院附属同仁医院骨科,上海200336

出　　处：《中华现代护理杂志》2025年第8期1052-1058,共7页Chinese Journal of Modern Nursing

基　　金：长宁区医学硕博士创新人才基地项目(RCJD2022S01)。

摘　　要：目的总结系统性红斑狼疮患者运动干预的最佳证据。方法采用澳大利亚乔安娜布里格斯研究所循证卫生保健中心的"PIPOST"模式构建循证护理问题,根据"6S"证据资源金字塔模型自上至下检索BMJ Best Practice、UpToDate、指南网站、专业协会网站及国内外中英文数据库中有关系统性红斑狼疮患者运动干预的临床指南、共识、系统评价、最佳实践、证据总结等相关证据。筛选符合质量标准的文献进行质量评价,提取证据。检索时限为建库至2024年6月15日。结果共纳入15篇文献,其中临床决策1篇,指南3篇,系统评价6篇,随机对照试验5篇。从运动原则、运动评估、运动方式、运动强度、运动频率和时间、运动监测6个方面汇总形成了25条证据。结论本研究汇总的系统性红斑狼疮患者运动干预的最佳证据,可为临床医务人员提供参考依据。ObjectiveTo summarize the best available evidence for exercise interventions in patients with systemic lupus erythematosus(SLE).MethodsThe PIPOST model from the Joanna Briggs Institute(JBI)Centre for Evidence-Based Healthcare in Australia was used to construct the evidence-based nursing question.A top-down approach based on the"6S"evidence pyramid model was employed to search for relevant evidence,including clinical guidelines,consensus statements,systematic reviews,best practices,and evidence summaries.The search was conducted across BMJ Best Practice,UpToDate,guideline repositories,professional association websites,and Chinese and international databases.Eligible literature was screened for quality assessment,and high-quality evidence was extracted.The search timeframe covered publications from database inception to June 15,2024.ResultsA total of 15 studies were included,comprising 1 clinical decision-making article,3 guidelines,6 systematic reviews,and 5 randomized controlled trials.A total of 25 evidence statements were synthesized across 6 key aspects:exercise principles,exercise assessment,exercise modalities,exercise intensity,exercise frequency and duration,and exercise monitoring.ConclusionsThe best evidence summarized in this study provides a valuable reference for clinical healthcare professionals implementing exercise interventions for patients with systemic lupus erythematosus.

关 键 词：系统性红斑狼疮 运动干预 循证护理 最佳证据 

分 类 号：R59[医药卫生—内科学]