青年颈椎病手术患者血脂水平、颈椎矢状力线参数与颈椎间盘退变的相关性  

Correlation between serum lipid level,sagittal force line parameters and cervical disc degeneration in young patients undergoing surgery for cervical spondylosis

作　　者：杨晓波 兰谢[1] YANG Xiaobo;LAN Xie(Department of Rehabilitation Medicine,Chengdu Third People's Hospital,Chengdu 610000)

机构地区：[1]成都市第三人民医院康复医学科,成都610000

出　　处：《颈腰痛杂志》2025年第1期74-78,共5页The Journal of Cervicodynia and Lumbodynia

摘　　要：目的分析青年颈椎病手术患者血脂水平、颈椎矢状力线参数与颈椎间盘退变的相关性。方法选择2018年1月至2021年6月于成都市第三人民医院骨科就诊的64例拟行颈椎病手术的青年患者作为研究对象,根据Pfirrmann分级总分,将患者分为两组,对比两组患者的血脂水平、颈椎矢状力线参数,评估两组患者的疼痛程度、神经功能症状、颈椎活动情况,分析血脂水平、颈椎矢状力线参数与患者颈椎间盘退变的相关性。结果轻度组患者的血清总胆固醇(TC)、三酰甘油(TG)水平,颈倾斜角(NT)、颈椎矢状面轴向垂直距离(C_(2-7)SVA)水平和视觉模拟(VAS)、颈椎总活动度(ROM)评分均明显低于中重度组,而轻度组患者的T1倾斜角(T1S)、颈椎前凸角(CLA)水平和日本骨科协会(JOA)评分明显高于中重度组,均有统计学差异(P<0.05)。轻度组患者的血清低密度脂蛋白(LDL)、高密度脂蛋白(HDL)水平和胸廓入口角(TIA)水平与中重度组相比,无统计学差异(P>0.05)。Pearson相关性分析结果显示,患者的LDL、HDL、TIA、T1S、NT水平与Pfirrmann分级总分无明显相关性(P>0.05);患者的TC、TG、C_(2-7)SVA水平与Pfirrmann分级总分呈正相关,CLA水平与Pfirrmann分级总分呈负相关(P<0.05)。结论青年颈椎手术患者的TC、TG、C_(2-7)SVA、CLA水平与其Pfirrmann分级总分有相关性,TC、TG、C_(2-7)SVA、CLA水平异常可加重颈椎间盘退变。但该研究中,样本量较小,数据存在一定不足。Objective To analyze the correlation between serum lipid level,sagittal force line and cervical disc degeneration in young patients with cervical spondylosis.Methods Sixty-four young patients undergoing cervical spondylosis surgery in the Department of Orthopedics of the Third People's Hospital of Chengdu from January 2018 to June 2021 were selected as the research subjects.According to the Pfirrmann graded total score,the patients were divided into two groups,and the blood lipid levels and cervical sagittal force line parameters of the two groups were compared.The pain degree,neurological symptoms and cervical vertebra activity were evaluated in two groups,and the correlation of blood lipid level,cervical sagittal force line parameters and cervical disc degeneration was analyzed.Results The serum total cholesterol(TC),triglyceride(TG)levels,neck tilt angle(NT),cervical spine sagittal vertical axis(C_(2-7)SVA)levels,and visual analogue scale(VAS),cervical range of motion(ROM)scores of patients in the mild group were significantly lower than those in the moderate to severe group,while the T1 slope(T1S),cervical lordosis angle(CLA)levels,and Japanese orthopaedic association(JOA)scores of patients in the mild group were significantly higher than those in the moderate to severe group,all with statistical differences(P<0.05).There was no statistical difference in the serum low-density lipoprotein(LDL),high-density lipoprotein(HDL)levels,and thoracic inlet angle(TIA)levels between the mild group and the moderate to severe group(P>0.05).Pearson correlation analysis results showed that there was no significant correlation between the patients′LDL,HDL,TIA,T1S,NT levels and the total Pfirrmann grading score(P>0.05);the patients′TC,TG,C_(2-7)SVA levels were positively correlated,and the CLA level was negatively correlated with the total Pfirrmann grading score(P<0.05).Conclusion The TC,TG,C_(2-7)SVA,CLA levels of young patients undergoing cervical spine surgery are correlated with the total Pfirrmann grading score,and a

关 键 词：颈椎病 血脂 颈椎矢状力线 颈椎间盘退变 Pfirrmann分级 颈椎总活动度 

分 类 号：R681.5[医药卫生—骨科学]