强直性脊柱炎合并Andersson lesion的研究进展  

Research progress of Andersson lesion in ankylosing spondylitis

作　　者：李文锋 张辉[1] LI Wenfeng;ZHANG Hui(Department of Spinal Orthopedics,The Affiliated Guangdong Second Provincial General Hospital of Jinan University,Guangzhou 510310)

机构地区：[1]暨南大学附属广东省第二人民医院脊柱骨科,广州510310

出　　处：《颈腰痛杂志》2025年第1期176-180,共5页The Journal of Cervicodynia and Lumbodynia

基　　金：广州市科技计划项目(202020230004)。

摘　　要：Andersson lesion(AL)是指发生在强直性脊柱炎晚期的病因尚未明确的并发症。目前的病因学说认为,脊柱慢性炎症和创伤后反复的机械应力共同作用导致假关节形成。诊断主要依据强直性脊柱炎病史及影像学表现。对于无脊柱不稳及神经功能损害的早期AL,优先考虑行保守治疗;而对于经保守治疗无效且严重后凸畸形伴神经损害的晚期AL常需要手术治疗,大多推荐一期单纯后路病灶清除截骨矫形植骨融合脊柱内固定术。Andersson lesion(AL)is a complication of ankylosing spondylitis with unknown etiology.Current etiological theories suggest that chronic inflammation of the spine and repeated mechanical stress after trauma act together to lead to pseudarthrosis.The diagnosis is mainly based on the history of ankylosing spondylitis and imaging findings.For early AL without spinal instability and neurological impairment,conservative treatment is preferred.However,for patients with severe kyphosis and neurological deficits who fail to respond to conservative treatment,surgical treatment is often required,and one-stage posterior debridement,osteotomy,bone grafting and spinal fusion are recommended.

关 键 词：强直性脊柱炎 Andersson lesion 脊柱畸形 脊柱后凸 病因学 手术治疗 

分 类 号：R681.5[医药卫生—骨科学]