基于MRI检测的脑结构参数对酒精所致精神病性障碍的诊断价值  

Diagnostic Value of MRI-Derived Cerebral Structural Parameters in Alcohol-Induced Psychotic Disorders

作　　者：张爱景 ZHANG Ai-jing(Department of Medical Imaging,Shangqiu City Second People’s Hospital,Shangqiu 476000,China)

机构地区：[1]商丘市第二人民医院影像科,河南商丘476000

出　　处：《实用临床医学(江西)》2025年第1期89-92,共4页Practical Clinical Medicine

摘　　要：目的 探究基于磁共振成像(MRI)检测的脑结构参数对酒精所致精神病性障碍患者的应用价值。方法回顾性纳入49例酒精所致精神病性障碍患者(观察组)与同期进行体检的49名无精神障碍者(对照组)为研究对象,患者均进行MRI扫描,收集其伏隔核体积、海马体积以及侧脑室颞角宽度、脑部病变等资料,并绘制受训者工作特征曲线(ROC曲线)判断MRI检查下脑部结构指标的诊断价值。结果 观察组患者的伏隔核体积、侧脑室颞角宽度均大于对照组(均P <0.01),海马体积小于对照组(P <0.01);观察组患者脑部病变的发生率高于对照组(63.27%比8.16%,P <0.001);ROC曲线显示,脑部结构参数的联合诊断曲线下面积(AUC值)为0.895(0.833~0.957),其诊断效能较高。结论 采用MRI检测能够直观反映酒精所致精神病性障碍患者的脑部结构异常变化及脑部病变情况,且伏隔核体积、侧脑室颞角宽度、海马体积对该病诊断具有一定的价值,联合诊断价值较高。Objective To investigate the clinical utility of MRI-derived brain structural parameters in patients with alcohol-induced psychotic disorders.Methods This retrospect-ive study enrolled 49 patients with alcohol-induced psychotic disorders(observation group)and 49 concurrently examined individuals without psychotic disorders(control group).All participants underwent MRI scans to quantify nucleus accumbens volume,hippocampal volume,temporal horn width of lateral ventricles,and incidence of cerebral lesions.Receiver operating characteristic(ROC)curve analysis was performed to evaluate the diagnostic efficacy of these structural indices.Results The observation group exhibited larger nucleus accumbens volumes(P<0.01)and temporal horn widths(P<0.01),but smaller hippocampal volumes(P<0.01)compared to controls.Cerebral lesions were more prevalent in the observation group(63.27%vs 8.16%,P<0.001).ROC analysis demonstrated that the combined diagnostic model yielded an area under the curve(AUC)of 0.895(95%CI:0.833–0.957),indicating robust diagnostic performance.Conclusion MRI demonstrates the capability to visualize cerebral structural abnormalities and cerebral lesions in patients with alcohol-induced psychotic disorders.Nucleus accumbens volume,temporal horn width,and hippocampal volume may serve as potential diagnostic markers,with enhanced efficacy when combined.

关 键 词：酒精所致精神病性障碍 磁共振成像 脑部结构异常 伏隔核体积 

分 类 号：R445.2[医药卫生—影像医学与核医学]