FAR、CAR、TyG指数、ALP及CHE联合检测诊断冠心病的效果探究  

Investigation on the value of combined detection of FAR,CAR,TyG index,ALP,and CHE in diagnosing coronary heart disease

作　　者：梁福燕 杨晓平 付爱丽 薛江楠[1] LIANG Fuyan;YANG Xiaoping;FU Aili;XUE Jiangnan(Department of Immunology,School of Basic Sciences,Binzhou Medical College,Yantai 264003,China;Laboratory Department,907 Hospital of the Joint Logistic Support Force,Yantai 264000,China)

机构地区：[1]滨州医学院基础学院免疫学教研室,山东烟台264003 [2]联勤保障部队第九七〇医院检验科,山东烟台264000

出　　处：《延边大学医学学报》2025年第1期45-47,共3页Journal of Medical Science Yanbian University

基　　金：山东省自然科学基金(编号:Y2007C009)。

摘　　要：目的:探究纤维蛋白原/白蛋白的比值(FAR)、C反应蛋白/白蛋白比值(CAR)、三酰甘油葡萄糖(Ty G)指数、碱性磷酸酶(ALP)及胆碱酯酶(CHE)联合检测诊断冠心病的效果。方法:选取2020年5月—2022年5月联勤保障部队第九七〇医院收治的160例冠心病患者为观察组,选取同时期的40例同龄健康者为对照组。比较两组及观察组不同血管狭窄程度者的FAR、CAR、Ty G指数、ALP及CHE水平,采用ROC分析FAR、CAR、Ty G指数、ALP及CHE联合检测诊断冠心病的效果。结果:观察组的FAR、CAR、Ty G指数、ALP及CHE水平高于对照组(P<0.05),观察组中不同血管狭窄程度者的上述检测结果比较,差异有统计学意义(P<0.05);ROC分析显示,联合检测冠心病的AUC值大于单项检测。结论:FAR、CAR、Ty G指数、ALP及CHE在冠心病患者中的表达相对异常,联合检测对冠心病的诊断价值较高。Objective:To explore the effect of combined detection of fibrinogen to albumin ratio(FAR),C-reactive protein to albumin ratio(CAR),triglyceride-glucose(TyG)index,alkaline phosphatase(ALP)and cholinesterase(CHE)in the patients with coronary heart disease.Methods:160 patients with coronary heart disease admitted to the 97th Hospital of the Joint Logistics Support Force from May 2020 to May 2022 were selected as the observation group,and 40 healthy individuals of the same age during the same period were selected as the control group.The FAR,CAR,TyG index,ALP and CHE of two groups and observation group with different degree of vascular stenosis were compared,and the effectiveness of combined detection of FAR,CAR,TyG index,ALP and CHE in diagnosing coronary heart disease were analyzed with ROC analysis.Results:The FAR,CAR,TyG index,ALP and CHE of the observation group were higher than those of the control group(P<0.05).The results of observation group with different degree of vascular stenosis were compared and the differences were statistically significant(P<0.05).The ROC analysis showed the area under curve(AUC)of combine detection were bigger than those of single detection.Conclusion:The expression of FAR,CAR,TyG index,ALP,and CHE is relatively abnormal in patients with coronary heart disease,and the combined detection has high diagnostic value for coronary heart disease.

关 键 词：冠心病 纤维蛋白原/白蛋白的比值 C反应蛋白/白蛋白比值 三酰甘油葡萄糖指数 碱性磷酸酶 胆碱酯酶 联合检测 

分 类 号：R446[医药卫生—诊断学]