紫锥菊活性成分菊苣酸的合成及调控研究进展  

Synthesis and Regulation Research Progress of Chicoric Acid,the Active Ingredient of Echinacea purpurea

作　　者：王子航 羽健宾 白玫[1,2] 吴鸿 梁祥修[1,2] 杨乔 WANG Zi-Hang;YU Jian-Bin;BAI Mei;WU Hong;LIANG Xiang-Xiu;YANG Qiao(College of Life Sciences,South China Agricultural University,Guangzhou 510642,China;Lingnan Modern Agriculture Science and Technology Laboratory,Guangzhou 510642,China)

机构地区：[1]华南农业大学生命科学学院,广州510642 [2]岭南现代农业科学与技术广东省实验室,广州510642

出　　处：《农业生物技术学报》2025年第3期659-669,共11页Journal of Agricultural Biotechnology

基　　金：国家自然科学基金(32270381);“十四五”广东省农业科技创新十大主攻方向“揭榜挂帅”项目(2022SDZG07)。

摘　　要：紫锥菊(Echinacea purpurea)是全世界范围广泛使用的一种极具经济价值的药用植物,具有增强免疫力、抗菌消炎等功效。菊苣酸是紫锥菊最主要的活性成分,也是评价药材质量的关键指标。菊苣酸的积累不仅受自身遗传因素的调控,光照、温度、微生物等环境因素对其合成和积累也有显著影响。本文主要阐述了紫锥菊及其活性成分的功效,并进一步讨论了主要活性成分菊苣酸的合成途径,从遗传特性和多种环境因子出发综述了对菊苣酸合成调控的机制,最后对合理提高紫锥菊活性成分积累的现状和应用前景进行展望。本文能够为紫锥菊资源的合理开发指明新的方向,也对提升药用植物品质与临床疗效有重要的意义。Echinacea purpurea is a widely used medicinal plant worldwide with significant economic value,known for its effects in enhancing immunity,antibacterial,and anti-inflammatory properties.The active ingredient chicoric acid is a crucial substance for exerting the medicinal effects of E.purpurea and serves as a key indicator for evaluating the quality of medicinal herbs.The production of active ingredients is not only regulated by its own genetic factors but is also significantly influenced by environmental factors such as light,temperature,and microorganisms in the synthesis and accumulation of active components in E.purpurea.This article mainly elucidated the efficacy of E.purpurea and its active ingredients,further discussed the synthetic pathways of the main active ingredient chicoric acid,summarized the regulatory mechanisms of the genetic characteristics and various environmental factors on the synthesis of chicoric acid,and finally provided an application outlook on the current status of enhance the accumulation of its active ingredients.This review provides new directions for the rational development of E.purpurea resources and is of great importance for improving the quality and clinical efficacy of medicinal plants.

关 键 词：紫锥菊 次生代谢产物 菊苣酸 合成调控 

分 类 号：S184[农业科学—农业基础科学]