四弯风汤治疗儿童特应性皮炎心火脾虚证的临床疗效研究  

The clinical effect of Siwanfeng decoction in treating atopic dermatitis with heart fire and spleen deficiency syndrome in children

作　　者：罗瑞静[1] 彭勇[1] 王英杰[1] 刘杰[1] 姜珠倩[1] 武宗琴 LUO Ruijing;PENG Yong;WANG Yingjie;LIU Jie;JIANG Zhuqian;WU Zongqin(Department of Dermatology,Jiading Hospital of Traditional Chinese Medicine,Shanghai 201899,China)

机构地区：[1]上海市嘉定区中医医院皮肤科,上海201899

出　　处：《世界临床药物》2025年第1期50-54,共5页World Clinical Drug

基　　金：上海市嘉定区卫健委项目(2020-KY-ZYY-08)。

摘　　要：目的探讨四弯风汤治疗儿童特应性皮炎(atopic dermatitis,AD)心火脾虚证的临床疗效。方法符合纳入标准的70例AD患者随机分为治疗组和对照组,每组各35例。治疗组给予四弯风汤口服,对照组给予盐酸左西替利嗪口服液口服,两组疗程均为6周。比较两组患者AD评分(scoring AD,SCORAD)变化情况及临床疗效。结果治疗组总有效率为97.14%,对照组总有效率为40%,治疗组总有效率显著高于对照组(P<0.001)。治疗后,治疗组SCORAD评分较治疗前及对照组降低,差异有统计学意义(P<0.001)。结论四弯风汤治疗儿童AD心火脾虚证有较好的临床疗效。Objective To explore the clinical efficacy of Siwanfeng decoction in treating atopic dermatitis(AD)in children with heart fire and spleen deficiency syndrome.Methods A total of 70 patients with AD who met the inclusion criteria were randomly divided into treatment group and control group,with 35 cases in each group.The treatment group was given Siwanfeng decoction orally,while the control group was given levocetirizine hydrochloride oral liquid orally.The treatment course was 6 weeks.The changes in scoring AD(SCORAD)scores and clinical efficacy were compared between two groups.Results The total effective rate of the treatment group was 97.14%and 40%in the control group,and the total effective rate of the treatment group was significantly higher than that of the control group(P<0.001).After treatment,the SCORAD score in the treatment group was decreased than before treatment and the control group,and the difference was statistically significant(P<0.001).Conclusion Siwanfeng decoction has a good clinical efficacy in treating children with AD with heart fire and spleen deficiency syndrome.

关 键 词：特应性皮炎 心火脾虚证 四弯风汤 

分 类 号：R751[医药卫生—皮肤病学与性病学] R275[医药卫生—临床医学]