“煨脓长肉”理念指导下用湿润烧伤膏促进慢性难愈性创面修复的疗效研究  

Efficacy of Moist Burn Ointment in Promoting Healing of Chronic Non-healing Wounds Under the Guidance of"Pus Stewing and Flesh Growing"Concept

作　　者：刘奕 向丽萍[2] LIU Yi;XIANG Liping(Department of Surgery,Hunan University of Traditional Chinese Medicine,Changsha 410005,China;Department of Wound Repair,The Second Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410005,China)

机构地区：[1]湖南中医药大学中医外科学,湖南长沙410005 [2]湖南中医药大学第二附属医院创面修复科,湖南长沙410005

出　　处：《中华灾害救援医学》2025年第1期49-52,73,共5页Chinese Journal of Disaster Medicine

基　　金：湖南省自然科学基金部门(A2023028)。

摘　　要：目的 分析在慢性难愈性创面修复中,在“煨脓长肉”理念指导下使用湿润烧伤膏的临床疗效。方法选取2022年9月至2024年5月湖南中医药大学第二附属医院收治的90例慢性难愈性创面患者为研究对象。根据随机数字表法,随机分为对照组(常规换药,45例)和观察组(湿润烧伤膏换药,45例)。比较伤口评估与效果评价量表(Bates-jensen Wound Assessment Tool,BWAT)评分、创面再上皮化(BWAT-1评分)、创面渗出情况(BWAT-2评分)、创面疼痛程度[视觉模拟评分法(visual analogue scale,VAS)]、细菌培养阳性率、临床疗效、安全性。结果 换药前,两组患者创面BWAT评分、BWAT-1评分、BWAT-2评分,疼痛程度VAS评分均无明显差异(P>0.05)。换药4周后,两组患者创面BWAT评分、BWAT-1评分、BWAT-2评分、VAS评分均较换药前显著降低(P<0.001);且与对照组相比,观察组各项评分更低(P<0.001)。换药4周后,两组患者细菌培养阳性率均较换药前显著降低(P<0.001)。观察组患者的临床治愈率和临床显效率明显更高(P<0.05)。结论 在慢性难愈性创面修复中,在“煨脓长肉”理念指导下用湿润烧伤膏可有效促进创面上皮化,控制创面渗出,抑制创面感染,减轻创面疼痛程度,促进创面愈合,提高创面治愈率。Objective To analyze the clinical efficacy of using moist burn ointment in the treatment of chronic non-healing wounds,guided by the concept of“simmering pus to promote granulation.”Methods Ninety patients with chronic non-healing wounds treated at the Second Affiliated Hospital of Hunan University of Chinese Medicine from September 2022 to May 2024 were selected for the study.Using a random number table method,the patients were randomly divided into a control group(conventional Western dressing changes,n=45)and an observation group(moist burn ointment dressing changes,n=45).Wound assessment was conducted using the Bates-Jensen Wound Assessment Tool(BWAT),which evaluates wound characteristics including re-epithelialization(BWAT-1),exudate(BWAT-2),pain intensity measured by the Visual Analogue Scale(VAS),bacterial culture positivity rate,clinical efficacy,and safety.Results Prior to treatment,there were no significant differences in BWAT scores,BWAT-1,BWAT-2 scores,or VAS pain scores between the two groups(P>0.05).After four weeks of treatment,all scores significantly decreased in both groups compared to baseline(P<0.001),with the observation group exhibiting significantly lower scores than the control group(P<0.001).The bacterial culture positivity rate also significantly decreased in both groups after four weeks(P<0.001).Furthermore,the clinical cure rate and clinical efficacy rate were significantly higher in the observation group(P<0.05).Conclusion The use of moist burn ointment guided by the concept of“simmering pus to promote granulation” effectively facilitates re-epithelialization, controls exudate, suppresses infection, alleviates pain, and promotes healing in chronic non-healing wounds, ultimately improving the wound cure rate.

关 键 词：创面 湿润烧伤膏 渗出 

分 类 号：R242[医药卫生—中医临床基础]