振腹推拿治疗餐后不适综合征伴不良情绪状态患者的临床疗效及对其胃功能的影响  

Clinical Efficacy of Vibratory Abdominal Massage in Treatment of Postprandial Distress Syndrome with Adverse Emotional State and Its Effect on Gastric Function

作　　者：刘杨 薛小娜[1] 吕亚楠 国生[1] 刘晓芳[1] 付国兵[1] 魏培栋[1] LIU Yang;XUE Xiao-na;LV Ya-nan;CUO Sheng;LIU Xiao-fang;FU Guo-bing;WEI Pei-dong(Dongfang Hospital,Beijing University of Chinese Medicine,Bejing 100078;Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100020)

机构地区：[1]北京中医药大学东方医院,北京100078 [2]北京中医药大学东直门医院,北京100020

出　　处：《世界中西医结合杂志》2025年第2期297-301,共5页World Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金委员会(82004422);2019年度基本科研业务费项目(2019-JYB-JS-118);北京中医药大学东方医院推拿诊疗中心重点专科项目(040203002003)。

摘　　要：目的观察振腹推拿治疗餐后不适综合征(Postprandial distress syndrome,PDS)伴不良情绪状态的临床疗效及对胃功能的影响。方法选取2019年5月1日—2022年5月30日期间北京中医药大学东方医院推拿科门诊收治的PDS伴焦虑患者94例作为研究对象。采用随机数字表法分为对照组和治疗组,每组各47例。对照组采用口服枸橼酸莫沙比利治疗,治疗组在对照组患者的基础上采用振腹推拿疗法治疗,两组均持续治疗4周。观察两组患者临床症状评分,治疗后临床疗效;比较两组患者治疗前后血清胃动力学指标[胃泌素17(Gastrin-17,G-17)、胃蛋白酶原Ⅰ(PepsinogenⅠ,PGⅠ)和胃蛋白酶原Ⅱ(PepsinogenⅡ,PGⅡ)]的变化,汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)和汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评分的变化;统计治疗期间两组患者的不良反应。结果治疗后治疗组临床总有效率95.74%(45/47)明显高于对照组82.98%(39/47),差异有统计学意义(P=0.047)。治疗后两组患者上腹灼热评分、食后腹胀不适、嗳气评分、早饱评分和胃纳减少评分均较治疗前降低,差异有统计学意义(P<0.05);且治疗组临床症状评分低于对照组,差异有统计学意义(P<0.05)。治疗后两组患者胃动力学指标G-17较治疗前降低,PGⅠ和PGⅡ较治疗前升高,差异有统计学意义(P<0.05);且治疗组G-17低于对照组,PGⅠ和PGⅡ高于对照组,差异有统计学意义(P<0.001)。治疗后两组患者HAMA、HAMD评分较治疗前降低,差异有统计学意义(P<0.05);且治疗组HAMA、HAMD评分低于对照组,差异有统计学意义(P<0.001)。治疗后治疗组不良反应总发生率12.77%(6/47)明显低于对照组31.91%(15/47),差异有统计学意义(P=0.026)。结论振腹推拿疗法可有效改善PDS症状,包括腹胀、早饱等,并有效缓解焦虑与抑郁,起到减少并发症的作用。Objective To observe the clinical efficacy of vibratory abdominal massage in the treatment of postprandial distress syndrome(PDS)with adverse emotional state and its effect on gastric function.Methods From May 1,2019 to May 30,2022,a total of 94 individuals diagnosed with PDS and anxiety were admitted to the Tuina Department of Dongfang Hospital,Beijing University of Chinese Medicine were selected as the research objects.According to the order of outpatient visits,they were divided into a control group and a treatment group by random number table method,with 47 cases in each group.The control group was treated with oral mosapride citrate,and the treatment group was treated with vibratory abdominal massage on the basis of the patients in the control group.The treatment lasted for four weeks.The clinical symptom scores and clinical efficacy of the two groups after treatment were recorded.The changes in serum gastrointestinal motility indicators[Gastrin-17(G-17),Pepsinogen I(PG I),and Pepsinogen I(PG I)]before and after treatment in both groups were compared,as well as the changes in the Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD)scores.In addition,the adverse reactions of the two groups during the treatment period were counted.Results After treatment,the total effective rate of the treatment group was 95.74%(45/47),which was significantly higher than that of the control group,82.98%(39/47),and the difference was statistically significant(P=0.047).Significant reductions were observed in the epigastric burning score,postprandial bloating and discomfort,belching score,early satiety score,and reduced appetite score among the patients in both groups(P<0.05),and the clinical symptom scores of the treatment group were lower than those of the control group(P<0.05).After treatment,the gastrointestinal motility indicator G-17 in the two groups was lower,and the PG I and PG I were higher than those before treatment(P<0.05).The levels of G-17 in the treatment group were lower than those in the control group

关 键 词：振腹推拿 餐后不适综合征伴 不良情绪 胃功能 

分 类 号：R244.1[医药卫生—针灸推拿学] R57[医药卫生—中医临床基础]