基于“脑-心-肾-精室”轴论治抑郁合并勃起功能障碍思路  

Ideas to Treat Depression Complicated with Erectile Dysfunction based on the"Brain-Heart-Kidney-Seminal Chamber"Axis

作　　者：骆第铖 张继伟[2] 王安民[2] 吴霜 赵子维 马东岳 刘洋 于文晓 郭军[2] LUO Di-cheng;ZHANG Ji-wei;WANG An-min;WU Shuang;ZHAO Zi-wei;MA Dong-yue;LIU Yang;YU Wen-xiao;GUO Jun(Graduate School of Beijing University of Chinese Medicine,Beijing 100029;Department of Andrology.Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091;Yunyang County Hospital of Traditional Chinese Medicine,Chongqing 404500)

机构地区：[1]北京中医药大学研究生院,北京100029 [2]中国中医科学院西苑医院男科,北京100091 [3]云阳县中医院,重庆404500

出　　处：《世界中西医结合杂志》2025年第2期402-406,共5页World Journal of Integrated Traditional and Western Medicine

基　　金：国家自然青年科学基金项目(82205134);中国中医科学院西苑医院提升中医药临床循证证据级别研究专项项目(XYZX020-06);国家自然科学基金面上项目(81873182);国家中医药管理局中医药传承与创新“百千万”人才工程岐黄学者资助项目(020450008);国家中医药管理局高水平中医药重点学科建设项目(zyyzdxk-2023238);成都中医药大学附属医院代谢性疾病中医药调控四川省重点实验室开放基金(SZKF202207)。

摘　　要：近年来抑郁合并勃起功能障碍(Erectile dysfunction,ED)的发病率不断增高,严重影响男性身心健康,家庭和睦。基于“脑-心-肾-精室”轴理论来认识抑郁合并ED的发病机理,认为脑-心-肾-精室功能失调是其发病之实质,其中脑心失调是发病之关键,精室失用是发病重要环节,肾元亏虚是发病之根本。脑心神明、肾元充盛、精室通利,阴茎方可勃起自如。对其治疗提出以“调”为法,整体辨证治疗,注重调畅情志,愉悦心脑;通调精室,振奋宗筋;调肾固本,济上滋下,临证整体用药以使脑-心-肾-精室功能恢复正常,从而抑郁得解,阳事可兴。In recent years,the incidence rate of depression complicated with erectile dysfunction(ED)has been increasing,seriously affecting the physical and mental health of males,as well as family harmony.Based on the theory of the"brain-heart-kidney-seminal chamber"axis,the pathogenesis of depression complicated with ED was understood.It is believed that the dysfunction of the brain-heart-kidney-seminal chamber is the essence of the pathogenesis.Among these,the brain-heart disharmony is the key,the seminal chamber dysfunction is an important link in the pathogenesis,and the renal element deficiency is the fundamental cause of the disease.The brain and heart control the mind,the renal element is full,and the seminal chamber is open,allowing the penis to erect freely.Thus,it is proposed to use"regulation"as the method for comprehensive treatment with syndrome differentiation.Specifically,attention should be paid to pleasing the heart and brain by regulating emotions;invigorating the zongjin by dredging and regulating the seminal chamber;and nourishing the upper and lower parts by regulating the kidney and consolidating the foundation.In clinical practices,medication covering the above aspects can restore normal brain-heart-kidney-seminal chamber function,thus relieving depression and promoting yang.

关 键 词：“脑-心-脑-精室”轴 勃起功能障碍 抑郁 思路 

分 类 号：R588.1[医药卫生—内分泌]