劳动年龄人口血尿酸与中医证型及体检指标的相关性分析  

Study on the Correlation Between Serum Uric Acid and TCM Syndromes and Physical Examination Indexes in Working-Age Population

作　　者：王源 魏珂 董晓阳 WANG Yuan;WEI Ke;DONG Xiaoyang(Department of Disease-Oriented Outpatient,Beijing Fengtai Hospital of Integrated Traditional Chinese and Modern Medicine,Beijing,100072 China;Department of Geriatrics,Beijing Fengtai Hospital of Integrated Traditional Chinese and Modern Medicine,Beijing,100072 China;Department of Physical Examination,Beijing Fengtai Hospital of Integrated Traditional Chinese and Modern Medicine,Beijing,100072 China)

机构地区：[1]北京市丰台中西医结合医院专病门诊,北京100072 [2]北京市丰台中西医结合医院老年病科,北京100072 [3]北京市丰台中西医结合医院体检中心,北京100072

出　　处：《中国医药指南》2025年第8期138-141,共4页Guide of China Medicine

基　　金：2022年院所协同创新科研专项基金(YS2022-11)。

摘　　要：目的研究劳动年龄人口血尿酸与中医证型及体检指标的相关性,分析影响血尿酸水平的危险因素。方法选取2018年1月至2022年8月北京市丰台中西医结合医院体检人群中1350例(经纳入与排除筛选后最终纳入1151例)体检者的数据资料,观察分析血尿酸与中医证型及体检指标的相关性。结果不同血尿酸水平的性别、年龄、腰围、BMI、收缩压、舒张压差异有统计学意义(P<0.05)。有痰湿证者血尿酸水平高于无痰湿证,而有阴虚证者血尿酸水平低于无阴虚证(P<0.05)。生化指标比较:血尿酸升高组的肌酐、尿素、同型半胱氨酸、谷草转氨酶、谷丙转氨酶、谷酰转肽酶、白蛋白、白球蛋白比、总胆固醇、甘油三酯、低密度脂蛋白11项指标数值水平更高,而高密度脂蛋白数值更低(均P<0.05)。通过二元Logistic回归分析,性别(OR=2.648,95%CI 1.049~6.685)、年龄(OR=0.967,95%CI 0.948~0.987)、腰围(OR=1.064,95%CI 1.041~1.088)、肌酐(OR=1.038,95%CI 1.022~1.053)、谷丙转氨酶(OR=1.011,95%CI 1.002~1.020)、甘油三酯(OR=1.489,95%CI 1.238~1.790)为血尿酸水平的独立影响因素(P<0.05),其对血尿酸水平升高的预测准确率为81.7%。结论痰湿证及阴虚证对血尿酸有影响。性别、年龄、腰围、肌酐、谷丙转氨酶、甘油三酯是血尿酸水平的独立影响因素,且预测准确度较高。Objective To study the correlation between serum uric acid and TCM syndromes and physical examination indexes in workingage population,and to analyze the risk factors affecting serum uric acid level.Methods A total of 1350 individuals who underwent physical examinations at the Fengtai Integrated Traditional Chinese and Western Medicine Hospital in Beijing from January 2018 to August 2022 were selected,and 1151 were finally included after screening based on inclusion and exclusion criteria.The data were analyzed to investigate the correlation between serum uric acid levels,traditional Chinese medicine(TCM)syndromes,and physical examination indicators.Results Differences in gender,age,waist circumference,BMI,systolic and diastolic blood pressure among different serum uric acid levels were statistically significant(P<0.05).Patients with phlegm-dampness syndrome had higher uric acid levels than those without,while patients with yin-deficiency syndrome had lower uric acid levels than those without(P<0.05).In biochemical comparisons,the elevated uric acid group had higher levels of creatinine,urea,homocysteine,AST,ALT,GGT,albumin,albumin-to-globulin ratio,total cholesterol,triglycerides,and LDL,but lower HDL levels(all P<0.05).Binary Logistic regression analysis identified gender(OR=2.648,95%CI 1.049-6.685),age(OR=0.967,95%CI 0.948-0.987),waist circumference(OR=1.064,95%CI 1.041-1.088),creatinine(OR=1.038,95%CI 1.022-1.053),ALT(OR=1.011,95%CI 1.002-1.020),and triglycerides(OR=1.489,95%CI 1.238-1.790)as independent predictors of elevated uric acid levels(P<0.05),with a prediction accuracy of 81.7%.Conclusions Phlegm Dampness Syndrome and Yin Deficiency Syndrome had influence on blood uric acid.Gender,age,waist circumference,creatinine,alanine aminotransferase and triglyceride were the independent influencing factors of serum uric acid level,and the prediction accuracy was high.

关 键 词：血尿酸 中医证型 体检指标 相关性分析 危险因素 

分 类 号：R589.7[医药卫生—内分泌]