西藏中老年人代谢综合征患病现状及危险因素分析  

Prevalence and risk factors of metabolic syndrome among middle-aged and elderly people in Tibet

作　　者：于跃 白国霞[2] 扎西宗吉[2] 史恒 彭介入 杨春霞 YU Yue;BAI Guo-xia;ZHAXI Zong-ji;SHI Heng;PENG Jie-ru;YANG Chun-xia(West China School of Public Health and West China Fourth Hospital,Sichuan University,Chengdu,Sichuan 610041,China;不详)

机构地区：[1]四川大学华西公共卫生学院/四川大学华西第四医院,四川成都610041 [2]西藏自治区疾病预防控制中心

出　　处：《现代预防医学》2025年第2期376-380,共5页Modern Preventive Medicine

基　　金：中央财政转移支付地方卫生计生项目—心血管病高危人群早期筛查与综合干预项目(2021—2022年)。

摘　　要：目的了解西藏地区中老年人代谢综合征(MS)的流行状况及其影响因素,为西藏地区制定并实施精准的MS的防控策略提供科学依据。方法2021年6月—2022年12月期间在西藏运用多阶段随机抽样的方法抽取6286名中老年人进行调查,使用SPSS 27.0软件对数据进行分析,利用χ^(2)检验及趋势性χ^(2)检验进行不同特征群体间的MS患病差异的比较,采用logistics回归模型进行MS患病的影响因素分析。结果在6286名中老年参与者中,筛查出MS患者共计1409例,总体患病率为22.41%;年龄越大,MS患病率越高(χ^(2)=49.694,P<0.001);男性MS患病率为27.8%,高于女性的18.21%,差异具有统计学意义(P<0.001)。多因素logistic回归分析结果显示,高龄(70岁及以上者OR=2.053,95%CI:1.545~2.728)、高血压家族史(OR=2.691,95%CI:2.293~3.158)、糖尿病家族史(OR=4.480,95%CI:2.066~9.716)以及体质指数(BMI)≥24.0 kg/m^(2)(OR=14.148,95%CI:11.778~16.995)为MS患病的危险因素,女性(OR=0.508,95%CI:0.443~0.584)、饮酒(OR=0.628,95%CI:0.487~0.812)为MS患病的保护因素。“血糖异常+血压异常+中心性肥胖”是MS异常组分组合中最普遍的聚集模式,患病率为5.41%。结论西藏地区中老年人MS患病率相对较高,其中男性、高龄者、具有高血压或糖尿病家族史以及超重肥胖人群应被视为MS防控的优先关注对象。Objective To comprehensively understand the incidence of metabolic syndrome(MS)and its potential risk elements in middle-aged and elderly people in Tibet,and to provide a scientific and reliable reference for the development and implementation of precise prevention and control strategies for MS in Tibet.Methods Between June 2021 and December 2022,6286 middle-aged and elderly people were strictly screened in Tibet by multi-stage stratified cluster random sampling.The data were organized and analyzed by using SPSS27.0 software,and the differences in MS prevalence among different groups were compared by using the chi-square test and the trend chi-square test,and further analyses of the factors affecting the prevalence of MS were conducted using logistics regression.Results Among 6286 middle-aged and elderly participants,a total of 1409 patients were screened,with an overall prevalence of metabolic syndrome of 22.41%,the older the age,the higher the prevalence of MS(SymbolcA@2=49.694,P<0.001);the prevalence of MS in men was 27.8%,higher than that in women,which was 18.21%,with a statistically significant difference(P<0.001).Multifactorial unconditional logistic regression analysis revealed that the main risk factors for the prevalence of MS were advanced age(OR=2.053,95%CI:1.545-2.728)for those aged 70 years and above,a family history of hypertension(OR=2.691,95%CI:2.293-3.158),a family history of diabetes(OR=4.480,95%CI:2.066-9.716)and a body mass index(BMI)≥24.0 kg/m^(2)(OR=14.148,95%CI:11.778-16.995),however,female(OR=0.508,95%CI:0.443-0.584)and alcohol consumption(OR=0.628,95%CI:0.487-0.812)were protective factors for the development of MS.In addition,among the various combinations of abnormal components of MS,the aggregation pattern of“abnormal glucose+abnormal blood pressure+central obesity”was the most prevalent,involving a total of 340 cases,with a prevalence rate of 5.41%.Conclusion The prevalence of MS in middle-aged and elderly people in Tibet is at a high level,in which males,elderly people,people w

关 键 词：代谢综合征 患病现状 影响因素 中老年人 西藏 

分 类 号：R589[医药卫生—内分泌]