蛋白A免疫吸附在肾移植中的应用进展  

Advances of protein A immunoadsorption in renal transplantation

作　　者：陈瑶(综述) 洪大情(审校)[1,2] CHEN Yao;HONG Daqing(School of Medicine,University of Electronic Science and Technology of China,Chengdu 610054,China;Department of Nephrology,Sichuan Academy of Medical Sciences,Sichuan Provincial People s Hospital,Chengdu 610072,China)

机构地区：[1]电子科技大学医学院,成都610054 [2]四川省医学科学院·四川省人民医院肾脏内科

出　　处：《肾脏病与透析肾移植杂志》2025年第1期91-95,共5页Chinese Journal of Nephrology,Dialysis & Transplantation

摘　　要：蛋白A免疫吸附是一种能清除患者体内致病性抗体的血液净化技术。该技术借助金黄色葡萄球菌蛋白A能特异性地与人体免疫球蛋白结合的特点,通过体外循环的方法,有效地清除致病抗体及其免疫复合物,具有较好的应用前景。随着技术的发展,免疫吸附越来越多地应用到肾移植的治疗中,但其有效性及安全性尚不明确。本文综述了蛋白A免疫吸附技术在肾移植中的应用情况,旨在为临床选择该项技术提供参考依据。Protein A immunoadsorption is a blood purification technique which removes pathogenic antibodies from the patient.It can effectively eliminate the pathogenic antibodies and immune complexes by extracorporeal circulation,which is characterized by the specific binding of Staphylococcus aureus protein A to human immunoglobulin,and it also has a great future for application.With the development of technology,immunoadsorption is increasingly used in the treatment of renal transplantation,but its effectiveness and safety are still unclear.This article will review the application of protein A immunoadsorption in renal transplantation,aiming to provide reference for the selection in clinical treatment.

关 键 词：蛋白A免疫吸附 肾移植 免疫吸附 

分 类 号：R699.2[医药卫生—泌尿科学]