磁性完全植入式静脉输液港的设计及动物实验  

Design and Animal Experiment of the Magnetic Totally Implantable Venous Access Port

作　　者：张莉[1] 张苗苗[1,2] 万嘉辉 湛启瑞 吕欣 吕毅[1,2] 严小鹏[1,2] ZHANG Lia;ZHANG Miaomiao;WAN Jiahui;ZHAN Qirui;LV Xin;LV Yi;YAN Xiaopeng(Department of Hepatobiliary Surgery,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an Shaanxi 710061,China;Shaanxi Provincial Key Laboratory of Magnetic Medicine,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an Shaanxi 710061,China;Zonglian College,Xi’an Jiaotong University,Xi’an Shaanxi 710061,China;Department of Pulmonary and Critical Care Medicine,The Second Affiliated Hospital of Xi’an Jiaotong University,Xi’an Shaanxi 710004,China)

机构地区：[1]西安交通大学第一附属医院肝胆外科,陕西西安710061 [2]西安交通大学第一附属医院陕西省磁医学重点实验室,陕西西安710061 [3]西安交通大学宗濂书院,陕西西安710061 [4]西安交通大学第二附属医院呼吸与危重症医学科,陕西西安710004

出　　处：《中国医疗设备》2025年第3期31-34,共4页China Medical Devices

基　　金：陕西省重点研发计划(2024SF-YBXM-447);陕西省自然科学基础研究计划(2023-JC-QN-0814);中央高校基本科研业务费专项资金(xzy022023068);西安交通大学第一附属医院科研发展基金(2022MS-07)。

摘　　要：目的为提高港针穿刺成功率,设计磁性完全植入式静脉输液港(Magnetic Total Implantable Venous Access Port,MTIVAP),并通过动物实验验证其可行性。方法根据磁锚定技术原理,通过在静脉输液港的港体中嵌入磁环,设计与之匹配的磁性定位装置,并完成MTIVAP的产品雏形设计。以4只比格犬为动物模型,在其颈部植入MTIVAP,5名实验人员分别在每只实验犬中进行港针穿刺10次,统计一次性插入成功率,验证MTIVAP在定位穿刺中的可行性。结果借助3D打印技术成功完成了MTIVAP的产品雏形制备。4只比格犬颈部均顺利植入MTIVAP。采用磁性定位装置后,在200次的穿刺过程中,港针一次性插入成功率达99.5%,操作体验得到了显著改善。结论MTIVAP的磁锚定设计方案能简化并显著改善港针的穿刺操作。Objective In order to improve the success rate of Huber needle puncture,to design a magnetic totally implantable venous access port(MTIVAP),and to verify its feasibility by animal experiments.Methods According to the principle of magnetic anchor technology,the magnetic positioning device was designed by embedding magnetic ring in the port body of the intravenous infusion port,and the product prototype of the MTIVAP was designed.A total of four beagle dogs were used as animal models to implant a MTIVAP in their necks,and five experimenters performed ten times piercings in each experimental dog,respectively.The success rate of onetime insertion was calculated to verify the feasibility of MTIVAP in positioning puncture.Results The prototype of the MTIVAP was successfully prepared using 3D printing technology.All four beagle dogs were successfully implanted with MTIVAP in their necks.After using the magnetic positioning device,the one-time insertion success rate of the Huber needle reached 99.5%in the course of 200 piercings,and the operating experience was significantly improved.Conclusion The design scheme of magnetic anchoring for MTIVAP can simplify and significantly improve the puncture operation of the Huber needle.

关 键 词：磁外科 磁锚定技术 完全植入式静脉输液港 港针 穿刺 磁环 比格犬 

分 类 号：R197.39[医药卫生—卫生事业管理] R608[医药卫生—公共卫生与预防医学]