FFR、CT-FFR及QFR在冠心病中的应用进展  

Application Progress of FFR,CT-FFR and QFR in Coronary Artery Revascularization

作　　者：田洋 刘晓林 TIAN Yang;LIU Xiaolin(Baotou School of Clinical Medicine,Inner Mongolia Medical University,Baotou Inner Mongolia 014040,China;Department of Imaging,Baotou Central Hospital,Baotou Inner Mongolia 014040,China)

机构地区：[1]内蒙古医科大学包头临床医学院,内蒙古包头014040 [2]包头市中心医院影像科,内蒙古包头014040

出　　处：《中国医疗设备》2025年第3期164-168,共5页China Medical Devices

基　　金：内蒙古自治区硕士研究生科学创新项目(S20231197Z)。

摘　　要：冠状动脉血运重建是治疗冠心病的有效方法,血流储备分数(Fractional Flow Reserve,FFR)是有创评估冠状动脉病变缺血的“金标准”,但需要额外的导丝及扩张血管,限制了临床的广泛使用。近年来,基于冠状动脉CT的FFR(FFR derived from Coronary CT Angiography,CT-FFR)、定量血流分数(Quantitative Flow Fraction,QFR)等新技术得到了迅速发展,能在避免使用额外导丝和扩展血管的同时,进一步评估心肌缺血的情况及冠状动脉狭窄程度。本文对FFR、CT-FFR及QFR的原理、应用价值及局限性等多个方面进行阐述,以期为临床医生在冠心病诊疗中选择合理技术提供参考。Coronary revascularization is an effective method for the treatment of coronary heart disease.Fractional flow reserve(FFR)is the gold standard for the invasive assessment of ischemia caused by coronary artery lesions.However,it requires additional guidewires and vasodilation,which limits its widespread clinical application.In recent years,new technologies such as FFR derived from coronary CT angiography(CT-FFR)and quantitative flow fraction(QFR)have developed rapidly.These technologies can further evaluate the situation of myocardial ischemia and the degree of coronary artery stenosis while avoiding the use of additional guidewires and vasodilation.This paper reviewed the principles,application values,and limitations of FFR,CT-FFR,and QFR from multiple aspects,aiming to provide a reference for clinicians to select reasonable technologies in the diagnosis and treatment of coronary heart disease.

关 键 词：血流储备分数 冠状动脉CT(CCTA) 定量血流分数 基于CCTA的血流储备分数 冠心病 冠状动脉血运重建 

分 类 号：R445.3[医药卫生—影像医学与核医学]