新型纳米材料用于动脉粥样硬化诊疗的研究进展  

Research progress on the application of novel nanomaterials in the diagnosis and treatment of atherosclerosis

作　　者：崔敏婕 彭跃有 孟延锋(审校) CUI Minjie;PENG Yueyou;MENG Yanfeng(School of Medical Imaging,Shanxi Medical University,Taiyuan 030607,China;Department of Radiology,Taiyuan Central Hospital of Shanxi Medical University)

机构地区：[1]山西医科大学医学影像学院,太原030607 [2]山西医科大学附属太原中心医院医学影像科

出　　处：《国际医学放射学杂志》2025年第2期210-213,238,共5页International Journal of Medical Radiology

基　　金：山西省基础研究计划资助项目(202103021224003);太原市卫生健康委员会“六个一批”项目(Z2022001)。

摘　　要：动脉粥样硬化(AS)的精准诊断和治疗是提高病人生存率的关键。目前通过集合靶向、示踪、治疗一体化的纳米材料可以获取更详细的影像学信息,实现精准靶向、局部治疗,在提高疗效的同时降低系统性治疗的毒副作用,对诊断及治疗AS有很好的应用前景。就一体化纳米材料在对AS不同病理阶段应用的研究进展予以综述。Precise diagnosis and treatment of atherosclerosis(AS)are crucial for improving patient survival rate.Currently,nanomaterials that integrate targeting,tracing,and therapeutic functions can provide more detailed imaging informations,enable precise targeting and localized treatment,enhance therapeutic efficacy,and reduce the systemic side effects of treatment.These nanomaterials shows great potential for the diagnosis and treatment of AS.This review summarizes the research progress on the application of integrated nanomaterials in different pathological stages of AS.

关 键 词：动脉粥样硬化 纳米材料 靶向递送 诊疗一体化 

分 类 号：R81[医药卫生—放射医学] R543.5[医药卫生—临床医学]