遵义市无偿献血人群高效价2019-nCoV IgG抗体筛查  

Screening of High-Titer IgG Antibodies to 2019-nCoV among Voluntary Blood Donors in Zunyi

作　　者：文良雪 苏丽[1] 曾胜军 张澜艺 黄四海 WEN Liang-Xue;SU Li;ZENG Sheng-Jun;ZHANG Lan-Yi;HUANG Si-Hai(Department of Clinical Laboratory,Zunyi Blood Center,Zunyi 563000,Guizhou Province,China)

机构地区：[1]遵义市中心血站检验科,贵州遵义563000

出　　处：《中国实验血液学杂志》2025年第2期526-529,共4页Journal of Experimental Hematology

摘　　要：目的:了解遵义市无偿献血人群中高效价2019-nCoV IgG抗体的血清学流行情况。方法:标本血浆按1∶160或1∶320稀释后用酶联免疫吸附实验间接法检测2019-nCoV IgG抗体,分析抗体反应性率在不同性别、年龄、血型中的差别。结果:5378份标本血浆按1∶160稀释后,筛查出1523份反应性标本;2988份标本血浆按1∶320稀释后,筛查出329份反应性标本。总的抗体反应性率为22.1%。进一步分析发现,女性、40岁以上、AB血型的人群中,高效价抗体反应性率相对较高。结论:新冠感染防控进入新阶段后,遵义市无偿献血人群中有较高的高效价2019-nCoV IgG抗体血清检出率。抗体反应性率在不同性别、年龄、血型间存在一定的差异。Objective:To investigate the serological prevalence of high-titer IgG antibodies against 2019-nCoV among voluntary blood donors in Zunyi.Methods:The blood plasma specimens were diluted at 1∶160 or 1∶320,then tested for the presence of 2019-nCoV IgG antibodies by using an indirect enzyme-linked immunosorbent assay(ELISA).The differences of antibody reactive rate among different genders,ages,and blood types were analyzed.Results:1523 reactive specimens were identified in 5378 specimens which were diluted at a ratio of 1∶160.Similarly,329 reactive specimens were identified in 2988 diluted at 1∶320.The overall reactive rate for antibodies was 22.1%.It was observed that females,individuals over the age of 40,and those with blood type AB exhibited higher high-titer antibody reactive rate.Conclusion:After entering a new stage of 2019-nCoV infection prevention and control,there is a relatively high detection rate of high-titer 2019-nCoV IgG antibodies among voluntary blood donors in Zunyi.The reactive rate of antibodies varies among different genders,ages,and blood types.

关 键 词：无偿献血者 新型冠状病毒 IGG抗体 

分 类 号：R446.6[医药卫生—诊断学]