超声波监测贴片换能器及血压动力学模型研究  

Ultrasonic monitoring patch transducer and dynamic model of blood pressure

作　　者：孙丰龙 李晓兵 杨钊萍 徐智阳 申春华 周长江 罗亚辉 聂生东[1] SUN Fenglong;LI Xiaobing;YANG Zhaoping;XU Zhiyang;SHEN Chunhua;ZHOU Changjiang;LUO Yahui;NIE Shengdong(School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China;Shanghai Jielu Biosensing Technology Co.,Ltd,Shanghai 201114;Department of Ultrasound,People's Hospital Affiliated to Shandong First Medical University,Jinan 271100,China)

机构地区：[1]上海理工大学健康科学与工程学院,上海200093 [2]上海捷鹿生物传感技术有限公司,上海201114 [3]山东第一医科大学附属人民医院超声科,济南271100

出　　处：《生物医学工程研究》2025年第1期31-36,共6页Journal Of Biomedical Engineering Research

基　　金：国家自然科学基金项目(52372119)。

摘　　要：血压监测对心血管疾病的早期预防和评估手术治疗效果具有重要作用。本研究采用超声技术探究了动脉直径与压力间的关系,设计并制备了厚度为2 mm的超声贴片换能器用于血压监测。该换能器的中心频率为10.4 MHz,插入损耗为6.3 dB。通过猪动脉离体实验,获得动脉直径与压力的相关数据。为描述动脉直径和血压之间的关系,基于Levenberg-Marquardt算法,建立了关于动脉直径的动力学模型。结果表明,该模型在血压低于183.75 mmHg时,具有较小的误差,平均绝对误差为2.2 mmHg。该模型有望应用于人体血压监测。Blood pressure monitoring plays an important role in the early prevention of cardiovascular diseases and in the evaluation of the effectiveness of surgical treatment.In order to investigate the relationship between arterial diameter and pressure,we used ultrasound technology to design an ultrasound patch transducer with a thickness of 2 mm for blood pressure monitoring.The center frequency of the transducer was 10.4 MHz,the insertion loss was 6.3 dB.The data on the relationship between arterial diameter and pressure were obtained from porcine arteries ex vivo.Using the Levenberg-Marquardt algorithm,a kinetic model of arterial diameter was obtained to describe the relationship between arterial diameter and blood pressure.The results showed that the model had a small error,with an average absolute error of 2.2 mmHg,in the range of blood pressure less than 183.75 mmHg.This model is expected to be applied to human blood pressure monitoring.

关 键 词：血压监测 超声换能器 超声贴片 血压动力学模型 LEVENBERG-MARQUARDT算法 超声技术 

分 类 号：R318[医药卫生—生物医学工程] TB552[医药卫生—基础医学]