基于伤口微环境智能调控的纤维材料  

Intelligent fibrous materials for wound microenvironment regulation

作　　者：吴金丹[1] WU Jindan(College of Textile Science and Engineering(International Institute of Silk),Zhejiang Sci-Tech University,Hangzhou 310018,China)

机构地区：[1]浙江理工大学纺织科学与工程学院(国际丝绸学院),浙江杭州310018

出　　处：《纺织高校基础科学学报》2025年第1期15-17,共3页Basic Sciences Journal of Textile Universities

摘　　要：社会老龄化的加剧导致慢性疾病高发,由此引发的慢性伤口问题日益严峻。这些伤口常伴随持续的炎症反应、高血糖环境诱发的细菌快速滋生以及过量渗液的产生,不仅延缓伤口愈合,还可能进一步引发感染和全身性并发症,严重威胁患者生命安全。伤口微环境变化直接影响创面愈合过程^([1-2]),而传统的伤口护理方法在微环境调控方面存在诸多局限性,难以满足慢性伤口治疗的复杂需求。本研究团队通过纤维结构设计实现微环境pH、湿度等重要因素的调控,进而促进伤口的抗感染和修复,为慢性伤口的精准管理与高效治疗提供创新性解决方案^([3]).With the intensification of societal aging leading to a high incidence of chronic diseases,the consequent issue of chronic wounds has become increasingly severe.These wounds are often accompanied by persistent inflammatory responses,rapid bacterial proliferation induced by hyperglycemic environments,and excessive exudate production,which not only delay wound healing but may also lead to infections and systemic complications,posing a serious threat to patient safety.Changes in the wound microenvironment directly affect the wound healing process^([1-2]),and traditional wound care methods have numerous limitations in microenvironment regulation,making it difficult to meet the complex needs of chronic wound treatment.Our research team has achieved regulation of critical factors such as pH and humidity in the microenvironment through the design of dressing structures,thereby promoting infection resistance and repair of wounds,providing innovative solutions for the precise management and efficient treatment of chronic wounds^([3]).

关 键 词：伤口微环境 智能纤维 纳米酶 长效抗菌 可控导液 

分 类 号：TS106.8[轻工技术与工程—纺织工程] R318.1[轻工技术与工程—纺织科学与工程]