督脉灸联合健步慢行对稳定期精神分裂症患者阴性症状、认知和社会功能的影响研究  

Impact of Du Meridian Moxibustion and brisk walking on negative symptoms,cognitive,and social functions in patients with stable schizophrenia

作　　者：曾钢[1] 曹伟烨 周文青 刘翠霞[4] 郑兴[5] 王雯 吴升伟[5] 陈晓东[4] Zeng Gang;Cao Weiye;Zhou Wenqing;Liu Cuixia;Zheng Xing;Wang Wen;Wu Shengwei;Chen Xiaodong(Department of Neuropsychiatry,the Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou 510370,,China;School of Nursing,Guangzhou Medical University,Guangzhou 510180,China;Department of Adult Psychiatry,the Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou 510370,China;Department of Chronic Diseases,the Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou 510445,China;Department of Traditional Chinese Medicine,the Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou 510445,China)

机构地区：[1]广州医科大学附属脑科医院精神神经科学病房,广州510370 [2]广州医科大学护理学院,广州510180 [3]广州医科大学附属脑科医院成人精神科,广州510370 [4]广州医科大学附属脑科医院慢性病科部,广州510445 [5]广州医科大学附属脑科医院中医科,广州510445

出　　处：《中国实用护理杂志》2025年第8期576-584,共9页Chinese Journal of Practical Nursing

基　　金：广东省中医药局科研项目(20232139)。

摘　　要：目的探究督脉灸联合健步慢行对稳定期精神分裂症患者阴性症状、认知和社会功能的临床应用效果,以期为临床提供切实可行的辅助治疗方案。方法采用随机对照试验,以便利抽样法选取2023年4月1日至2024年3月31日在广州医科大学附属脑科医院住院治疗的稳定期精神分裂症患者140例作为研究对象。采用随机字母生成器随机分为对照组、督脉灸组、健步慢行组、联合组各35例。对照组给予常规护理,在常规护理的基础上,督脉灸组给予艾灸督脉,健步慢行组给予慢步行走,联合组给予艾灸督脉联合慢步行走。干预12周。比较干预前,干预后第6、12周及干预结束后第12周时4组的阴性症状量表、简易精神状态量表和住院精神病患者社会功能评定量表评分。结果研究最终纳入134例患者,其中对照组34例,督脉灸组34例,健步慢行组35例,联合组31例。对照组男15例,女19例,年龄(53.52±9.24)岁,督脉灸组男18例,女16例,年龄(52.82±9.29)岁,健步慢行组男16例,女19例,年龄(54.48±7.40)岁,联合组男13例,女18例,年龄(51.71±9.03)岁。干预第12周和干预结束后第12周时联合组的阴性症状量表得分分别为(49.71±4.66)分和(53.45±5.34)分,优于督脉灸组的(54.91±4.79)、(59.56±5.84)分,健步慢行组的(56.69±5.59)、(58.51±5.42)分和对照组的(65.71±4.95)、(66.21±4.33)分,差异均有统计学意义(t值为3.81~13.37,均P<0.05)。联合组在干预第12周和干预结束后第12周时联合组的简易精神状态量表评分分别为(28.23±1.28)、(27.35±1.76)分,高于督脉灸组的(26.79±1.85)、(25.59±2.27)分,健步慢行组的(25.88±2.23)、(25.43±1.84)分和对照组的(23.65±2.17)、(22.32±2.14)分,差异均有统计学意义(t值为-10.28~-3.48,均P<0.001)。联合组在干预第12周和干预结束后第12周时住院精神病患者社会功能评定量表评分分别为(35.71±3.63)、(32.58±3.71)分,高于督脉灸组的(32.21±3.91)、(Objective To investigate the clinical effectiveness of Du Meridian moxibustion combined with brisk walking on negative symptoms,cognitive function,and social function in patients with stable schizophrenia,aiming to provide a feasible adjunctive treatment for clinical practice.Methods A randomized controlled trial was conducted using convenience sampling to recruit 140 patients with stable schizophrenia hospitalized at the Affiliated Brain Hospital of Guangzhou Medical University from April 1,2023,to March 31,2024.Patients were randomly assigned to a control group,Du Meridian moxibustion group,brisk walking group,or combined group,with 35 patients in each group.The control group received standard care.On this basis,the Du Meridian moxibustion group received moxibustion on the Du Meridian,the brisk walking group participated in slow walking exercises,and the combined group received both interventions for 12 weeks.Assessments were conducted at baseline,at 6 and 12 weeks during the intervention,and at 12 weeks post-intervention using the Scale for the Assessment of Negative Symptoms,Mini-Mental State Examination,and Social Functioning Scale for Inpatient Psychiatric Patients.Results A total of 134 patients completed the study:control group(n=34),Du Meridian moxibustion group(n=34),brisk walking group(n=35),and combined group(n=31).The combined group demonstrated significantly lower SANS scores at the 12th week of intervention(49.71±4.66)and at 12 weeks post-intervention(53.45±5.34)compared to the Du Meridian moxibustion group(54.91±4.79)and(59.56±5.84),the brisk walking group(56.69±5.59)and(58.51±5.42),control group(65.71±4.95)and(66.21±4.33),with statistically significant differences(t values were 3.81-13.37,all P<0.05).Regarding cognitive function,the MMSE scores in the combined group at the 12th week of intervention(28.23±1.28)and at 12 weeks post-intervention(27.35±1.76)were higher than those in the Du Meridian moxibustion group(26.79±1.85)and(25.59±2.27)and the brisk walking group(25.88±2.23)and(25.

关 键 词：督脉灸 有氧运动 康复 精神分裂症 阴性症状 认知功能 社会功能 

分 类 号：R24[医药卫生—中医临床基础]