Hydrogel-filled micropipette enables antifouling in vivo iontronic sensing  

水凝胶填充微米管实现活体抗污染离电传感

作　　者：Guangguo Guo Yifei Pan Tianyi Xiong Wenliang Ji Wenjie Ma Ping Yu Yuqing Lin Lanqun Mao 郭广国;潘亦菲;熊天逸;纪文亮;马文杰;于萍;林雨青;毛兰群

机构地区：[1]Beijing National Laboratory for Molecular Science,Key Laboratory of Analytical Chemistry for Living Biosystems,Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190,China [2]College of Chemistry,Beijing Normal University,Beijing 100875,China [3]Department of Chemistry,Capital Normal University,Beijing 100048,China [4]University of Chinese Academy of Sciences,Beijing 101408,China

出　　处：《Science Bulletin》2025年第4期469-473,共5页科学通报(英文版)

基　　金：financially supported by the Beijing Natural Science Foundation(Z230022 for Ping Yu,2242028 for Wenjie Ma);the National Natural Science Foundation of China(22125406 and 22074149 for Ping Yu,22074095 and 22374103 for Yuqing Lin);the National Basic Research Program of China(2022YFA1204500,2022YFA1204503 to Ping Yu).

摘　　要：lontronic sensors,based on sophisticated control of ion concentration,depletion,and flow,have attracted considerable research attention because of their high compatibility with constructed human-machine interfaces[1-3].Especially,iontronic sensors constructed of confined nano/micropipettes can realize biomolecule dynamic detection of dopamine[4],adenosine triphosphate[5],and hydrogen peroxide[6].These pipette-confined iontronic sensors have significant advantages for implantable in vivo sensing because of their high spatiotemporal resolution and robust implantable tips[7].However,the nonspecific adsorption of proteins onto the sensing interface largely limits their application to in vivo sensing.

关 键 词：enable FILLED FOULING 

分 类 号：TP2[自动化与计算机技术—检测技术与自动化装置]