结直肠癌中医证候与术后病理相关性研究  

Study on the Correlation between Traditional Chinese Medicine Syndrome and Postoperative Pathology in Colorectal Cancer

作　　者：李伟婷 彭辉 沈毅[2] 刘举达[2] 王振[2] 经文善 于庆生[2] LI Weiting;PENG Hui;SHEN Yi;LIU Juda;WANG Zhen;JING Wenshan;YU Qingsheng(Anhui University of Chinese Medicine,Anhui Hefei 230031,China;The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Anhui Hefei 230031,China)

机构地区：[1]安徽中医药大学第一临床医学院,安徽合肥230031 [2]安徽中医药大学第一附属医院,安徽合肥230031

出　　处：《中医药临床杂志》2025年第3期532-536,共5页Clinical Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金:(编号:82174160,82374208);十二五国家临床重点专科建设项目(财社[2013]239号);十二五国家中医药管理局重点专科建设项目(国中医药医政发[2012]2号)。

摘　　要：目的:该研究通过横断面研究,系统总结结直肠癌患者的临床病理特征,探讨其与中医证候的相关性,为中医药在结直肠癌诊疗中的应用提供理论依据,为临床诊疗提供参考。方法:该研究采用回顾性分析的方法,收集了272例结直肠癌患者的详细临床资料,包括一般情况、临床表现、肿瘤病理特征等,并通过中医辨证,对结直肠癌患者进行了证候分类,将其分为实证和虚证两种类型,建立了结直肠癌临床信息数据库。运用卡方检验分析结直肠癌患者证候与术后病理特征的相关性。结果:患者的性别、肿瘤组织学类型、肿瘤大体分型、肿瘤部位、淋巴结是否转移与中医证候无统计学意义,患者的年龄、原发肿瘤的解剖位置、肿瘤的分化程度以及病理分期患者的年龄、原发肿瘤的解剖位置、肿瘤的分化程度以及病理分期与中医证候有统计学意义。结论:结直肠癌患者的性别、肿瘤的组织学类型、肿瘤的大体分型、肿瘤部位以及淋巴结是否转移等因素与结直肠癌的证候分布的相关性较弱,而患者的年龄、原发肿瘤的解剖位置、肿瘤的分化程度以及病理分期等因素与结直肠癌证候的分布之间存在一定的相关性。Objective:This study,through a cross-sectional study,systematically summarizes the clinicopathologi-cal characteristics of colorectal cancer patients,explores their correlation with traditional Chinese medicine(TCM)syndromes,provides a theoretical basis for the application of TCM in the diagnosis and treatment of colorectal can-cer,and offers a reference for clinical diagnosis and treatment.Methods:This study adopted a retrospective analysis method,collecting detailed clinical data of 272 colorectal cancer patients,including general conditions,clinical manifestations,and tumor pathological characteristics.Through traditional Chinese medicine(TCM)syndrome dif-ferentiation,the colorectal cancer patients were classified into two types:excess syndrome and deficiency syndrome,and a clinical information database of colorectal cancer was established.The chi-square test was used to analyze the correlation between the syndromes of colorectal cancer patients and their postoperative pathological characteristics.Results:The patient's gender,tumor histological type,gross tumor type,tumor location,and lymph node metastasis were not statistically significant with the TCM syndrome.The patient's age,anatomical location of the primary tumor,tumor differentiation,and pathological stage were statistically significant with the TCM syndrome.Conclusion:The fac-tors such as the patient's gender,tumor histological type,gross tumor type,tumor location,and lymph node metasta-sis have a relatively weak correlation with the distribution of syndromes in colorectal cancer patients.However,factors such as the patient's age,anatomical location of the primary tumor,tumor differentiation,and pathological stage have a certain correlation with the distribution of syndromes in colorectal cancer.

关 键 词：结直肠癌 中医证候 术后病理 病理相关性 

分 类 号：R273[医药卫生—中西医结合]