药学干预前后Ⅱ类切口围手术期预防使用抗菌药物的情况及效果  

Effect of perioperative prophylactic use of antibiotics in Class II incision before and after pharmaceutical intervention

作　　者：刘怀珠 黄晓燕 靳蓉 申键 Liu Huai-zhu;Huang Xiao-yan;Jin Rong;Shen Jian(Department of Pharmacy,Luoyang Maternal and Child Health Hospital,Luoyang 471000,Henan,China)

机构地区：[1]洛阳市妇幼保健院药学部,河南洛阳471000

出　　处：《四川生理科学杂志》2025年第3期588-591,共4页

摘　　要：目的:分析药学干预前后Ⅱ类切口围手术期预防使用抗菌药物的情况及应用效果。方法:回顾性收集2023年7月至2024年8月期间本院收治的87例接受隐匿性阴茎延长术治疗的患者临床资料,按照药物干预方式分为对照组(常规诊疗服务,n=31)与研究组(接受药学干预,n=56)。分析比较两组的抗菌药物预防使用情况、抗菌药物预防使用时间与疗程、预防使用抗菌药物费用、抗菌药物使用合理性以及术后切口感染发生情况。结果:两组的抗菌药物预防使用率均为100%。对照组抗菌药物以β内酰胺酶抑制剂为主,研究组抗菌药物均使用头孢二代,两组抗菌药物品种使用选择有显著差异(P<0.05)。两组的抗菌药物预防时机无显著差异(P>0.05)。研究组抗菌药物费用显著低于对照组(P<0.05)。研究组的抗菌药物使用不合理总发生率显著低于对照组(P<0.05)。两组在术后均未出现切口感染情况。结论:药学干预可促进本院Ⅱ类切口围手术期预防使用抗菌药物的合理应用,缩短抗菌药物疗程,减少用药费用。Objective:To analyze the perioperative prophylactic use of antibiotics in class II incision before and after pharmaceutical intervention.Methods:The clinical data of 87 patients who underwent concealed penis lengthening from July 2023 to August 2024 in our hospital were retrospectively collected.According to the drug intervention methods,the patients were divided into the control group(routine diagnosis and treatment services,n=31)and the study group(pharmaceutical intervention,n=56).The prophylactic use of antibiotics,the time and course of prophylactic use of antibiotics,the cost of prophylactic use of antibiotics,the rationality of the use of antibiotics and the incidence of postoperative incision infection were analyzed.Results:The prophylactic use rate of antibiotics was 100%in both groups.β-lactamase inhibitors were the main antimicrobials in the control group,while cephalosporin II was used in the study group.There were significant differences in the selection of antimicrobials between the two groups(P<0.05).There was no significant difference in the timing of antibiotic prevention between the two groups(P>0.05).The cost of antibiotics in the study group was significantly lower than that in the control group(P<0.05).The total incidence of irrational use of antibiotics in the study group was significantly lower than that in the control group(P<0.05).No incision infection occurred in both groups after surgery.Conclusion:Pharmaceutical intervention can promote the rational use of antibiotics for perioperative prophylactic use in Class II incisions,shorten the course of antibiotics and reduce the cost of drugs.

关 键 词：药学干预 Ⅱ类切口 抗菌药物 围手术期 预防用药 

分 类 号：R47[医药卫生—护理学]