马来酸麦角新碱辅助缩宫素预防剖宫产后宫缩乏力性产后出血的效果及对患者血压、Hb的影响  

Effect of ergometrine maleate assisted with oxytocin on preventing postpartum hemorrhage caused by uterine inertia after cesarean section and its influence on blood pressure and Hb

作　　者：郑美容 Zheng Mei-rong(Department of Obstetrics and Gynecology,Yiyang People's Hospital,Shangrao 334400,Jiangxi,China)

机构地区：[1]弋阳县人民医院妇产科,江西上饶334400

出　　处：《四川生理科学杂志》2025年第3期651-653,共3页

摘　　要：目的:探究马来酸麦角新碱辅助缩宫素预防剖宫产后宫缩乏力性产后出血的效果及对患者血压、血红蛋白(Hemoglobin,Hb)的影响。方法:将本院2021年5月至2023年5月收治的70例剖宫产单胎足月分娩产妇按照采用的药物不同进行分组,其中采用缩宫素预防的34例产妇纳入对照组,在缩宫素基础上辅助使用马来酸麦角新碱预防的36例纳入联合组。比较两组产妇术后2h、术后24h的出血量、产后出血发生率、血液中纤维蛋白原含量和安全性。结果:联合组产妇术后2 h和术后24 h出血量均少于对照组(P<0.05)。联合组产后出血发生率明显低于对照组(P<0.05)。术后24h,两组的Hb、纤维蛋白原均升高(P<0.05),其中联合组Hb和纤维蛋白原均水平高于对照组(P<0.05)。两组间术前、术后24h的收缩压、舒张压水平无明显差异。两组不良反应总发生率差异不具有统计学意义。结论:在剖宫产后宫缩乏力性产后出血的预防中联合使用缩宫素与马来酸麦角新碱,能有效减少术后出血量,降低产后出血发生率,改善凝血功能,且安全性较好。Objective:To investigate the effect of ergometrine maleate assisted with oxytocin on the prevention of postpartum hemorrhage caused by uterine inertia after cesarean section and its influence on blood pressure and hemoglobin(Hb)in patients.Methods:From May 2021 to May 2023,70 cesarean section puerpera with singleton full-term delivery in the hospital were grouped according to different drugs.34 cases adopted oxytocin for prevention were included in control group,and 36 cases who were assisted with ergometrine maleate on the basis of oxytocin for prevention were enrolled as combined group.The bleeding volumes at 2 and 24 hours after surgery,incidence rate of postpartum hemorrhage,blood fibrinogen content and safety were compared between groups.Results:The bleeding volumes at 2 hours and 24 hours after surgery in combined group were less than those in control group(P<0.05).The incidence rate of postpartum hemorrhage was significantly lower in combined group than that in control group(P<0.05).The levels of Hb and fibrinogen in both groups were increased at 24 hours after surgery(P<0.05),and the levels in combined group were higher than those in control group(P<0.05).The systolic blood pressure and diastolic blood pressure revealed no obvious differences before surgery and at 24 hours after surgery between the two groups.The total incidence rate of adverse reactions was not statistically different between groups.Conclusion:Combined application of oxytocin and ergometrine maleate for the prevention of postpartum hemorrhage caused by uterine inertia after cesarean section can effectively reduce the postoperative bleeding volume,lower the incidence rate of postpartum hemorrhage,and improve the coagulation function,with good safety.

关 键 词：血压 血红蛋白 马来酸麦角新碱 缩宫素 宫缩乏力 产后出血 价值 

分 类 号：R47[医药卫生—护理学]