经胸超声心动图在系统硬化症相关肺动脉高压早期筛查及治疗前、后的应用价值  

Application Value of Transthoracic Echocardiography in Early Screening,Pre-and Posttreatment of Pulmonary Arterial Hypertension Associated with Systemic Sclerosis

作　　者：胡海 万青 王铮 周子鹏 HU Hai;WAN Qing;WANG Zheng;ZHOU Zipeng(Ultrasound Department,Henan Provincial Hospital of Traditional Chinese Medicine(Second Affiliated Hospital of Henan University of Chinese Medicine),Henan 450002,China;Rheumatology Department,Henan Provincial Hospital of Traditional Chinese Medicine(Second Affiliated Hospital of Henan University of Chinese Medicine),Henan 450002,China)

机构地区：[1]河南省中医院(河南中医药大学第二附属医院)超声科,河南450002 [2]河南省中医院(河南中医药大学第二附属医院)风湿科,河南450002

出　　处：《影像技术》2025年第2期8-11,共4页Image Technology

基　　金：河南省中医药科学研究专项课题(2018ZY2048)。

摘　　要：目的:探讨经胸超声心动图在系统性硬化症相关肺动脉高压早期筛查及治疗前后的应用价值。方法:选取符合系统性硬化症诊断标准患者59例,收集患者的临床资料,根据超声心动图检查是否合并肺动脉高压,分为不伴肺动脉高压组和伴有肺动脉高压组,比较两组在性别、年龄、病程、临床特征及治疗前、后经胸超声心动图等指标的变化情况。结果:两组在性别、年龄、病程上无统计学意义(P>0.05);而在雷诺现象、呼吸道症状,食管钡餐检查及治疗前、后肺动脉收缩压值与心包积液上存在差异性(P<0.05),患者的关节症状及射血分数无统计学意义(P>0.05)。结论:经胸超声心动图不仅能早期预估系统硬化症是否合并肺动脉高压,而且能够有效评估治疗前、后期的肺动脉压及心包积液等情况,为临床指导合理用药提供可靠的保障,使系统性硬化症合并肺动脉高压患者的存活率和生活质量均有所改善,值得临床早期筛查运用。Objective:To investigate the application value of transthoracic echocardiography in the early screening,pre-and post-treatment of pulmonary arterial hypertension associated with systemic sclerosis.Methods:Fifty-nine patients who met the diagnostic criteria for systemic sclerosis were selected,and their clinical data were collected.The patients were divided into two groups based on whether or not they had pulmonary arterial hypertension according to transthoracic echocardiography.The changes in gender,age,disease duration,clinical features,and transthoracic echocardiographic indicators before and after treatment were compared between the two groups.Results:There were no statistically significant differences between the two groups in terms of gender,age,and disease duration(P>0.05).However,there were significant differences in Raynaud's phenomenon,respiratory symptoms,esophageal barium meal examination,posterrior pulmonary artery systolic pressure values,and pericardial effusion before and after treatment(P<0.05).There were no statistically significant differences in joint symptoms and ejection fraction between the two groups(P>0.05).Conclusion:Transthoracic echocardiography can not only predict early whether systemic sclerosis is associated with pulmonary arterial hypertension,but also effectively assess the pulmonary artery pressure and pericardial effusion before and after treatment,providing a reliable guarantee for clinical guidance on rational drug use.This can improve the survival rate and quality of life of patients with systemic sclerosis and pulmonary arterial hypertension,and is worthy of early clinical screening and application.

关 键 词：系统性硬化症 经胸超声心动图 肺动脉高压 

分 类 号：R445.1[医药卫生—影像医学与核医学]