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作 者:王文爽 刘静[1] 滕金轩 何川 李倩[1] WANG Wenshuang;LIU Jing;TENG Jinxuan;HE Chuan;LIQian(Epilepsy Center,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)
机构地区:[1]首都医科大学附属北京天坛医院癫痫中心,北京100070
出 处:《癫痫杂志》2025年第2期168-171,184,共5页Journal of Epilepsy
基 金:国家自然科学基金资助项目(82071457)。
摘 要:癫痫持续状态根据发作形式和脑电图表现可分为惊厥性癫痫持续状态(convulsive status epilepticus,CSE)和非惊厥性癫痫持续状态(nonconvulsive status epilepticus,NCSE)。NCSE患者有明确的脑电图异常表现,但不伴典型的惊厥性抽搐,仅可见意识状态改变或轻微运动症状。由于其临床症状不典型,NCSE极易延误诊断或误诊、漏诊,从而造成NCSE患者不可逆的脑组织损伤,出现严重的意识功能和行为障碍,甚至引起死亡。临床积极预防发作、早期识别症状,规范化治疗对改善NCSE患者预后具有重要意义。目前尚未形成NCSE诊疗护理的相关规范、共识。文章报道一例首都医科大学附属北京天坛医院癫痫中心2024年6月21日收治的伴意识障碍的非惊厥性癫痫持续状态患者,经精准化治疗和护理,患者症状控制良好、病情稳定,出院后随访1个月,预后较好,以期为相关疾病的临床护理提供一定参考。According to their seizure patterns and EEG findings,status epilepticus can be divided into convulsive status epilepticus(CSE)and nonconvulsive status epilepticus(NCSE).Patients with NCSE have well-established EEG abnormalities without typical convulsive convulsions and only altered mental status or mild motor symptoms.Due to its atypical clinical symptoms,NCSE is prone to delayed diagnosis,misdiagnosis,or missed diagnosis,resulting in irreversible brain tissue damage,severe impairment of consciousness,function,and behavior,and even death in NCSE patients.It is of great significance to actively prevent seizures,identify symptoms early,and standardize treatment to improve the prognosis of NCSE patients.At present,there is no relevant standard and consensus on NCSE diagnosis and care.Here,we reported a patient with NCSE who admitted to the Epilepsy Center of Beijing Tiantan Hospital on June 21,2024.After precise treatment and nursing,the patient's symptoms were well controlled,his condition was stable,and he was followed up for 1 month after discharge,and the prognosis was good.This case report aimed to provide some clinical suggestions to relateddisease.
关 键 词:局灶性癫痫 非惊厥性癫痫持续状态 意识障碍 护理
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