Additive Manufacturing Technology Lends Wings to Orthopedic Clinical Treatment-The Innovative Development of Medical Additive Manufacturing in Shanghai Ninth People’s Hospital  

作　　者：Wei Yang Shasha Liu Liang Deng Dinghao Luo Zhaoyang Ran Tinglong Chen Lei Wang Kai Xie Junxiang Wu Wenbo Jiang Ping Liu Jingke Fu Yongqiang Hao Kerong Dai 

机构地区：[1]Shanghai Engineering Research Center of Innovative Orthopaedic Instruments and Personalized Medicine,Clinical and Translational Research Center for 3D Printing Technology,Shanghai,200011,China [2]The Base of Achievement Transformation,Shidong Hospital Affiliated to University of Shanghai for Science and Technology,Shanghai,200443,China [3]Shanghai Key Laboratory of Orthopaedic Implant,Department of Orthopaedic Surgery,Shanghai Ninth People’s Hospital Shanghai Jiao Tong University School of Medicine,Shanghai,200011,China

出　　处：《Additive Manufacturing Frontiers》2024年第4期44-56,共13页增材制造前沿(英文)

基　　金：supported by National Natural Science Foundation of China(Grant No.82273489);National Key Research&Develop-ment Program of China(Grant No.2022YFC2406000);Shanghai Municipal Key Clinical Specialty(Grant No.shslczdzk06701);the Biomaterials and Regenerative Medicine Institute Cooperative Research Project,Shanghai Jiao Tong University School of Medicine(Grant No.2022LHA01).

摘　　要：3D-printing technology,a leading example of advanced additive manufacturing,has revolutionized the treatment of clinical orthopedic diseases,ushering in a new era of personalized medicine.Since the 1980s,the orthopedic team led by Prof.Kerong Dai at Shanghai Ninth People’s Hospital,affiliated with Shanghai Jiao Tong University School of Medicine,has effectively advanced the research,development,and implementation of customized artificial joints through medical collaboration.This work laid the foundation for the application of domestic 3D-printing in orthopedics.Continuous innovations-from fundamental research to clinical practice,from metal prosthesis implantation to customized bioactive bone product replacement,and from the traditional standardized diagnostic and treatment paradigm to the transformation of personalized medical models-underscore the pivotal role of 3D-printing technology.It has promoted personalized medicine,enhanced surgical precision,minimized the risk of infection,and accelerated bone integration.Prof.Yongqiang Hao’s group has further expanded and deepened the application of three-dimensional printing technology in orthopedics.Significant breakthroughs have been achieved in domestic bioactive metals,metal orthopedic implants,and 3D-printed biological implants.The protocols for personalized internal fixation and novel pelvic reconstruction prostheses are now internationally recognized in clinical practice.This study provides a comprehensive overview of the innovative research and applications of personalized and customized 3D-printed orthopedic implants.

关 键 词：Additive manufacturing 3D bioprinting Alloys IMPLANTS PERSONALIZATION Clinical transformation 

分 类 号：F42[经济管理—产业经济]