Biofabrication:Bioprinting Process,Printing Materials,and the Frontier Applications in Biomedicine  

作　　者：Yuxiang Qin Linlin Fan Lei Zhan Jiayi Sun Jianhong Liu Canyu Gao Sisi Ma Xiaobing Pu Li Zhao Ying Zheng Lihua Jiang Changchun Zhou Yujiang Fan 

机构地区：[1]College of Biomedical Engineering,National Engineering Research Center for Biomaterials,Sichuan University,Chengdu,610064,China [2]Department of health Policy and Management,West China School of Public Health and West China Fourth Hospital,Teaching&Research Section of General Practice,The General Practice Medical Center,Sichuan University,Chengdu,610041,China [3]West China School of Public Health and West China Fourth Hospital,Sichuan University,Chengdu,610064,China [4]Department of Applied Biology and Biotechnology,Hong Kong Polytechnic University,Hong Kong,999077,China [5]Department of Obstetrics and Gynecology,West China Second Hospital,Chengdu,610041,China

出　　处：《Additive Manufacturing Frontiers》2024年第4期102-114,共13页增材制造前沿(英文)

基　　金：supported by National Key Research and Development Program of China(Grant Nos.2023YFC2411300,2023YFB4605800);National Natural Science Foundation of China(Grant No.32471474);Sichuan Science and Technology Program(Grant Nos.2024YFHZ0125,2022NSFSC1405);China Postdoctoral Science Foundation(Grant No.2022M722268);Research and Develop Program,West China Hospital of Stomatology Sichuan University(Grant No.RD-03-202406).

摘　　要：Biofabrication,also known as bioprinting,has been widely used in the field of biomedicine.The three most important factors in biofabrication are 3D bioprinter,biomaterials to be printed(bioinks),and the printing object(application).This review provides a detailed introduction to the latest research progress in these aspects.In particularly,the bioinks for bioprinting require strict biocompatible requirements.Four typical materials,i.e.metal/alloys,ceramics,polymers,and their composites,were introduced in detail,and their printing process and application scenarios were summarized,respectively.There are many applications of biofabrication in clinical practice.The application of biofabrication in skeletal system,skin and soft tissue,cardiovascular system,digestive system,respiratory system,urinary system,nervous system,plastic surgery and medical aesthetics were briefly introduced.The applications of biofabrication has a wide range of clinical need.Biofabrication is an innovative technology that is expected to further promote the clinical precision treatments.

关 键 词：BIOFABRICATION Bioprinting process Printing materials Frontier applications 

分 类 号：TG1[金属学及工艺—金属学]