咽喉反流相关嗓音疾病的声学特征与危险因素分析  

Analysis on Acoustic Characteristics and Risk Factors of Voice Disorders Associated with Laryngopharyngeal Reflux

作　　者：张帆[1] 余鹏[1] 李健玉 胡洪义[1] 张菁菁[1] ZHANG Fan;YU Peng;LI Jianyu;HU Hongyi;ZHANG Jingjing(Department of Otolaryngology,Peking University Shenzhen Hospital,Shenzhen 518036,China)

机构地区：[1]北京大学深圳医院耳鼻咽喉科,广东深圳518036

出　　处：《临床医学工程》2025年第2期213-216,共4页Clinical Medicine & Engineering

基　　金：深圳大学耳鼻喉科学科建设项目(项目编号:01)。

摘　　要：目的分析咽喉反流相关嗓音疾病的声学特征及危险因素。方法选取我院耳鼻喉科2022年5月至2024年5月确诊为咽喉反流相关嗓音疾病的50例患者作为观察组,另选取同期我院无咽喉反流相关嗓音疾病的50例健康体检者作为对照组。分析咽喉反流相关嗓音疾病的声学特征以及危险因素。结果观察组Jiiter、Shimmer、NHR明显高于对照组,MPT、DSI明显低于对照组(P<0.05)。咽喉反流相关嗓音疾病的发生与性别、长期喊叫、用嗓时间、吸烟、饮酒、上消化道疾病史、胃食管反流病史、管教幼儿、有毒物质接触史有关(P<0.05)。咽喉反流患者DSI评分与Jitter、Shimmer、NHR、RSI呈负相关,与MPT呈正相关(P<0.001)。结论咽喉反流相关嗓音疾病患者存在明显的嗓音异常,提示可能存在声带病变。咽喉反流相关嗓音疾病的危险因素较多,其发生与女性、长期喊叫、用嗓时间、吸烟、饮酒、上消化道疾病史、胃食管反流病、管教幼儿、有毒物质接触等密切相关。Objective To analyze the acoustic characteristics and risk factors of voice disorders associated with laryngopharyngeal reflux.Methods 50 patients diagnosed as voice disorders associated with laryngopharyngeal reflux in our Department of Otorhinolaryngology from May 2022 to May 2024 were selected as the observation group,and 50 people without voice disorders associated with laryngopharyngeal reflux during the same period were selected as the control group.The acoustic characteristics and risk factors of voice disorders associated with laryngopharyngeal reflux were analyzed.Results The Jiiter,Shimmer and NHR of the observation group were significantly higher than those of the control group,and the MPT and DSI were significantly lower than those of the control group(P<0.05).The occurrence of voice disorders associated with laryngopharyngeal reflux was correlated with the gender,prolonged shouting,voice use time,smoking,alcohol consumption,history of upper gastrointestinal disease,history of gastroesophageal reflux disease,disciplining children,and toxic exposure(P<0.05).DSI score of patients with laryngopharyngeal reflux was negatively correlated with Jitter,Shimmer,NHR and RSI,and positively correlated with MPT(P<0.001).Conclusions Patients with voice disorders associated with laryngopharyngeal reflux have significant voice abnormalities,suggesting possible vocal cord pathology.There are more risk factors for voice disorders associated with laryngopharyngeal reflux,among which female,prolonged shouting,voice use time,smoking,alcohol consumption,history of upper gastrointestinal diseases,history of gastroesophageal reflux disease,disciplining children,and toxic exposure are closely related to the occurrence of disease.

关 键 词：咽喉反流 嗓音疾病 声学特征 危险因素 

分 类 号：R767.92[医药卫生—耳鼻咽喉科]