低频重复经颅磁刺激联合旋律语调疗法对脑卒中后语言障碍患者的疗效分析  

Effect Analysis of Low-frequency Repetitive Transcranial Magnetic Stimulation Combined with Melodic Intonation Therapy in Patients with Post-stroke Speech Disorder

作　　者：康硕 施旭 李松岩 戴迪迪 房效莉 KANG Shuo;SHI Xu;LI Song-yan;DAI Di-di;FANG Xiao-li(Department of Rehabilitation Medicine,Xuzhou Municipal Hospital Affiliated to Xuzhou Medical University,Xuzhou First People's Hospital,Xuzhou,Jiangsu,221000,China;Department of Rehabilitation Medicine,Xuzhou First People's Hospital,Xuzhou,Jiangsu,221000,China;Department of Rehabilitation Medicine,The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,221000,China;Department of Neurology,The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,221000,China)

机构地区：[1]徐州医科大学附属徐州市立医院,徐州市第一人民医院康复医学科,江苏徐州221000 [2]徐州市第一人民医院康复医学科,江苏徐州221000 [3]徐州医科大学附属医院康复医学科,江苏徐州221000 [4]徐州医科大学附属医院神经内科,江苏徐州221000

出　　处：《现代生物医学进展》2025年第4期640-647,共8页Progress in Modern Biomedicine

基　　金：江苏省高校自然科学研究面上项目(24KJB320022)。

摘　　要：目的:分析低频重复经颅磁刺激联合旋律语调疗法对脑卒中后语言障碍患者的疗效.方法:选择自2022.12-2024.11收治的81例脑卒中后语言障碍患者,随机分为A组、B组和C组,每组各27例.A组予以常规治疗;B组在常规治疗的基础上,予以低频重复经颅磁刺激;C组在常规治疗的基础上,予以低频重复经颅磁刺激联合旋律语调疗法治疗;均连续治疗4周.采用西方失语症成套测验(WAB)对自发语、听理解、复述和命名进行评估,同时比较两组治疗前后的失语商(AQ值)、操作商(PQ值)、非言语认知量表(NLCA)评分、波士顿诊断性失语症检查(BDAE)分级.结果:C组治疗后自发言语、听理解、复述和命名的评分均高于A组和B组(P<0.05);C组治疗后AQ值和PQ值均大于A组和B组,NLCA评分高于A组和B组(P<0.05);C组治疗后BDAE分级优于A组和B组(P<0.05);C组治疗有效率为74.07%,高于A组的48.15%和B组的51.85%(P<0.05).结论:低频重复经颅磁刺激联合旋律语调疗法可改善语言功能,相比常规疗法能更显著提高疗效.Objective:To analyze the efficacy of low-frequency repetitive transcranial magnetic stimulation combined with melodic intonation therapy in patients with post-stroke language disorder.Methods:81 patients with post-stroke language disorder admitted to our hospital from December 2022 to November 2024 were selected as the study objects and randomly divided into group A,group B and group C,with 27 cases in each group.Group A was given routine treatment;Group B was given low frequency repetitive transcranial magnetic stimulation on the basis of conventional treatment;On the basis of conventional treatment,group C was treated with low-frequency repetitive transcranial magnetic stimulation combined with melodic intonation therapy.All were treated continuously for 4 weeks.Spontaneous speech,comprehension,paraphrasing,and naming were assessed using the Western Aphasia Battery Test(WAB).The scores of aphasia quotient(AQ),operator(PQ),non-verbal Cognition Scale(NLCA),Boston Diagnostic Aphasia Test(BDAE).Results:The scores of spontaneous speech,comprehension,repetition and naming in group C were higher than those in group A and group B(P<0.05).AQ and PQ values of group C after treatment were higher than those of group A and group B,NLCA score was higher than those of group A and group B(P<0.05).The BDAE classification of group C after treatment was better than that of group A and group B(P<0.05).The effective rate of group C was 74.07%,which was higher than that of group A(48.15%)and group B(51.85%)(P<0.05).Conclusion:Low-frequency repetitive transcranial magnetic stimulation combined with melodic intonation therapy can further improve the speech function,and can significantly improve the efficacy compared with conventional therapy.

关 键 词：脑卒中 语言障碍 低频重复经颅磁刺激 旋律语调疗法 语言功能 

分 类 号：R3[医药卫生—基础医学] R493