经颅直流电刺激联合感觉统合训练对孤独症谱系障碍患儿的康复效果研究  

Study on the Rehabilitation Effect of Transcranial Direct Current Stimulation Combined with Sensory Integration Training on Children with Autism Spectrum Disorder

作　　者：周祯优 方维影 李志敏 柳蔓 代珂鑫 ZHOU Zhen-you;FANG Wei-ying;LI Zhi-min;LIU Man;DAI Ke-xin(Children's Rehabilitation Center,The Second Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang,Guizhou,550003,China)

机构地区：[1]贵州中医药大学第二附属医院儿童康复中心,贵州贵阳550003

出　　处：《现代生物医学进展》2025年第4期699-705,共7页Progress in Modern Biomedicine

基　　金：贵州省卫生健康委员会科学技术基金项目(黔卫健函[2023]1-416)。

摘　　要：目的:探讨经颅直流电刺激(tDCS)联合感觉统合训练对孤独症谱系障碍(ASD)患儿的康复效果.方法:采用随机数字表法将我院2023年1月到2024年6月期间收治的80例ASD患儿分为对照组(接受感觉统合训练,n=40)和研究组(接受tDCS联合感觉统合训练,n=40).比较两组治疗前后两组患儿的儿童孤独症评定量表(CARS)、孤独症行为量表(ABC)、孤独症治疗评估表(ATEC)、格赛尔(Gesell)发育量表各项评分、听觉诱发失匹配负波(MMN)的幅值、潜伏期.结果:研究组治疗后的CARS、ABC、ATEC评分低于对照组(P<0.05).研究组治疗后的个人-社交行为、语言行为、精细动作行为、大运动行为及适应性行为评分高于对照组(P<0.05).研究组治疗后的听觉诱发MMN的幅值高于对照组,潜伏期低于对照组(P<0.05).结论:tDCS联合感觉统合训练可有效改善ASD患儿的临床症状,提升患儿对听觉信息的加工能力,促进患儿生长发育.Objective:To explore the rehabilitation effect of transcranial direct current stimulation(tDCS)combined with sensory integration training on children with autism spectrum disorder(ASD).Methods:The random number table method was used,80 ASD children who were admitted to our hospital from January 2023 to June 2024 were divided into control group(received sensory integration training,n=40)and study group(received tDCS combined with sensory integration training,n=40).The scores of Childhood Autism Rating Scale(CARS),Autism Behavior Scale(ABC),Autism Treatment Evaluation Scale(ATEC),Gesell(Gesell)development scale,the amplitude and latency of auditory evoked mismatch negativity(MMN)were compared between two groups before and after treatment.Results:The CARS,ABC and ATEC scores in study group were lower than those in control group after treatment(P<0.05).The scores of personal-social behavior,language behavior,fine motor behavior,big movement behavior and adaptive behavior in study group were higher than those in control group after treatment(P<0.05).The amplitude of auditory evoked MMN in study group was higher than that in control group after treatment,and the latency was lower than that in control group(P<0.05).Conclusion:tDCS combined with sensory integration training can effectively improve the clinical symptoms of ASD children,improve the processing ability of auditory information,and promote the growth and development of children.

关 键 词：儿童 孤独症谱系障碍 感觉统合训练 经颅直流电刺激 康复效果 

分 类 号：R3[医药卫生—基础医学] R493