宫腔镜电切术联合孕三烯酮治疗子宫内膜息肉的临床效果  

Clinical Effect of Hysteroscopic Electric Resection and Gestrinone in the Treatment of Endometrial Polyps

作　　者：田星 TIAN Xing(Beijing Huairou Hospital,Beijing 101400,China)

机构地区：[1]北京怀柔医院,北京101400

出　　处：《中外医学研究》2025年第7期16-19,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨子宫内膜息肉(EP)患者采用宫腔镜电切术联合孕三烯酮治疗的临床效果。方法:选取2021年1月—2024年1月北京怀柔医院收治的66例EP患者,以随机数表法分为研究组(n=33)与对照组(n=33)。对照组给予宫腔镜电切术治疗,研究组给予宫腔镜电切术联合孕三烯酮治疗。比较两组临床疗效、子宫内膜厚度、月经量、雌激素受体(ER)、孕激素受体(PR)、痛经程度、性生活质量。结果:研究组治疗总有效率较对照组高,差异有统计学意义(P<0.05)。两组术后3个月子宫内膜厚度变薄,月经量减少,研究组子宫内膜厚度较对照组薄,月经量少,差异有统计学意义(P<0.05)。两组术后3个月ER、PR均下降,且研究组ER、PR较对照组低,差异有统计学意义(P<0.05)。两组术后3个月视觉模拟评分法(VAS)评分均下降,且研究组VAS评分较对照组低,差异有统计学意义(P<0.05)。两组术后3个月女性性功能指数量表(FSFI)评分均升高,且研究组FSFI评分较对照组高,差异有统计学意义(P<0.05)。结论:宫腔镜电切术联合孕三烯酮应用于EP患者治疗中,能够提高临床疗效,使子宫内膜变薄,减少月经量,降低雌孕激素受体,缓解痛经程度,提高性生活质量。Objective:To explore the clinical effect of hysteroscopic electric resection and Gestrinone in the treatment of patients with endometrial polyps(EP).Method:A total of 66 patients with EP from January 2021 to January 2024 admitted in Beijing Huairou Hospital were selected,and they were randomly divided into study group(n=33)and control group(n=33)by random number table method.The control group treated with hysteroscopic electric resection.The study group treated with hysteroscopic electric resection and Gestrinone.The clinical efficacy,endometrial thickness,menstrual volume,estrogen receptor(ER),progesterone receptor(PR),degree of dysmenorrhea pain,quality of sexual life in both groups were compared.Result:The total effective rate of the study group was higher than that of the control group,the difference was statistically significant(P<0.05).At 3 months after surgery,the endometrial thickness of the two groups were thinner and the menstrual volume decreased,the endometrial thickness of the study group was thinner than that of the control group,and the menstrual volume was less,the differences were statistically significant(P<0.05).At 3 months after surgery,ER and PR decreased in both groups,and ER and PR in the study group were lower than those in the control group,the differences were statistically significant(P<0.05).The visual analogue scale(VAS)scores of both groups decreased at 3 months after surgery,and VAS score of study group was lower than control group,the differences were statistically significant(P<0.05).At 3 months after surgery,female sexual function index scale(FSFI)scores of both groups were increased,and FSFI scores of study group were higher than those of control group,the differences were statistically significant(P<0.05).Conclusion:The combination of hysteroscopic electric resection and Gestrinone in the treatment of EP patients can improve clinical efficacy,thin the endometrium,reduce menstrual flow,lower estrogen and progesterone receptors,alleviate dysmenorrhea,improve sexual quality of lif

关 键 词：宫腔镜电切术 孕三烯酮 子宫内膜息肉 临床效果 

分 类 号：R71[医药卫生—妇产科学]