宫腔镜子宫内膜息肉电切术联合屈螺酮炔雌醇治疗子宫内膜息肉患者的效果  

Effect of Hysteroscopic Transcervical Resection of Polyps Combined with Drospirenone Ethinylestradiol in the Treatment of Patients with Endometrial Polyps

作　　者：刘阳[1] LIU Yang(Xuzhou Maternal and Child Health Hospital,Xuzhou 221000,China)

机构地区：[1]徐州市妇幼保健院,江苏徐州221000

出　　处：《中外医学研究》2025年第7期42-45,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨宫腔镜子宫内膜息肉电切术(TCRP)联合屈螺酮炔雌醇治疗子宫内膜息肉患者的效果。方法:选取2022年7月—2023年7月徐州市妇幼保健院收治的100例子宫内膜息肉患者作为研究对象,采取随机数表法分为观察组与对照组,各50例。对照组实施宫腔镜TCRP治疗,观察组实施宫腔镜TCRP联合屈螺酮炔雌醇片(Ⅱ)治疗。对比两组临床疗效、治疗前后子宫内膜厚度、月经失血图评分,治疗前、治疗后3个月肝肾功能、凝血功能。结果:观察组治疗总有效率高于对照组,治疗后子宫内膜厚度、月经失血图评分低于对照组,差异有统计学意义(P<0.05);两组治疗前、治疗后3个月谷丙转氨酶、谷草转氨酶、肌酐、D-二聚体水平比较,差异无统计学意义(P>0.05)。结论:宫腔镜TCRP联合屈螺酮炔雌醇治疗子宫内膜息肉患者可提高临床效果,缩小子宫内膜厚度,减少月经量,且安全性高,并未引起肝肾及凝血功能等异常。Objective:To investigate the effect of hysteroscopic transcervical resection of polyps(TCRP)combined with Drospirenone Ethinylestradiol in the treatment of patients with endometrial polyps.Method:A total of 100 patients with endometrial polyps who admitted to Xuzhou Maternal and Child Health Hospital from July 2022 to July 2023 were selected as the research objects,they were divided into the observation group and the control group by random number table method,with 50 cases in each group.The control group was treated with hysteroscopic TCRP,and the observation group was treated with hysteroscopic TCRP combined with Drospirenone Ethinylestradiol Tablets(Ⅱ).The clinical efficacy,endometrial thickness and menstrual bleeding score before and after treatment,liver and kidney function and coagulation function before treatment and 3 months after treatment were compared between two groups.Result:The total effective rate of the observation group was higher than that of the control group,and the endometrial thickness and menstrual blood loss score after treatment were lower than those of the control group,the differences were statistically significant(P<0.05);there were no significant differences in the levels of alanine aminotransferase,aspartate aminotransferase,creatinine and D-dimer between two groups before treatment and 3 months after treatment(P>0.05).Conclusion:Hysteroscopic TCRP combined with Drospirenone Ethinylestradiol in the treatment of patients with endometrial polyps can improve the clinical effect,reduce endometrial thickness,reduce menstrual volume,and has high safety,and does not cause liver and kidney,coagulation function and other abnormalities.

关 键 词：宫腔镜 子宫内膜息肉电切术 子宫内膜息肉 屈螺酮炔雌醇 内膜厚度 肝肾功能 凝血功能 

分 类 号：R713.4[医药卫生—妇产科学]