腹腔镜卵巢囊肿剔除术对OMA伴/不伴DIE患者远期预后的影响  

Effect of laparoscopic ovarian cyst removal on the long⁃term prognosis of OMA in patients with/without DIE

作　　者：张立[1] 代先琼 任秀聪 Zhang Li;Dai Xianqiong;Ren Xiucong(Department of Obstetrics and Gynecology,Chengdu Integrated Traditional Chinese and Western Medicine Hospital,Chengdu Sichuan 610000,P.R.China)

机构地区：[1]成都市中西医结合医院妇产科,四川成都610000

出　　处：《中国计划生育和妇产科》2025年第1期67-71,共5页Chinese Journal of Family Planning & Gynecotokology

摘　　要：目的分析腹腔镜卵巢囊肿剔除术对卵巢子宫内膜异位囊肿(ovarian endometrioma,OMA)伴/不伴深部浸润型子宫内膜异位症(deep infiltrating endometriosis,DIE)患者远期预后的影响。方法回顾性分析2015年10月至2016年10月成都市中西医结合医院收治的120例OMA患者的临床资料。根据患者是否伴有DIE分为OMA+DIE组(60例)与OMA组(60例)。所有患者均实施腹腔镜卵巢囊肿剔除术治疗,比较两组临床疗效、疼痛情况、卵巢功能、肿瘤标志物、性生活质量及术后1年、3年、5年的疼痛、囊肿复发及成功妊娠情况。结果OMA组手术总有效率(100.00%)与OMA+DIE组(98.33%)比较,差异无统计学意义(P>0.05);OMA+DIE组术前痛经、腹痛、性交痛评分高于OMA组,FSFI量表各维度评分低于OMA组(P<0.05),术后痛经、腹痛、性交痛评分及FSFI量表各维度评分均优于术前,但两组间上述指标比较,差异无统计学意义(P>0.05);OMA+DIE组术前FSH、LH、E2及CA125、HE4、EMAb水平高于OMA组(P<0.05),术后FSH、LH、E2及CA125、HE4、EMAb水平均优于术前,但两组上述指标比较,差异无统计学意义(P>0.05);OMA+DIE组与OMA组术后1年、3年、5年疼痛复发率、囊肿复发率、妊娠成功率比较,差异无统计学意义(P>0.05)。结论腹腔镜卵巢囊肿剔除术有利于改善OMA或OMA伴DIE患者的卵巢功能、性生活质量,减轻疼痛程度,抑制病情进展,且能获得较为相似的远期预后。Objective To analyze the impact of laparoscopic ovarian cysts removal on the long-term prognosis of ovarian endometrioma(OMA)in patients with/without deep infiltrating endometriosis(DIE).Methods The clinical data of 120 OMA patients admitted to Chengdu Integrated Traditional Chinese and Western Medicine Hospital from October 2015 to October 2016 were retrospectively analyzed.Patients were divided into OMA+DIE group(60 cases)and OMA group(60 cases)according to whether they were accompanied by DIE.AIl patients were treated with laparoscopic ovarian cyst removal.The clinical efficacy,pain,ovarian function,tumor markers,sexual life quality pain and cyst recurrence at 1,3 and 5 years afer surgery,and successful pregnancy were compared between the two groups.Results The total effective rate in OMA group was not significantly difference from that in the OMA+DIE group(100.00%vs.98.33%,P>0.05).The preoperative dysmenorhea,abdominal pain and dyspareunia scores of the OMA+DIE group were higher than those of the OMA group,and the scores of each dimension of the FSFI scale were lower than those of the OMA group(P<0.05).The scores of dysmenorrhea,abdominal pain,dyspareunia and all dimensions of FSFI scale after operation were better than those before operation,but there was no statistical significance in the above indexes between the two groups(P>0.05).The levels of FSH,LH,E2,CA125,HE4 and EMAb in OMA+DIE group before surgery were higher than those in OMA group(P<0.05),and the levels of FSH,LH,E2,CA125,HE4 and EMAb aftersurgery were better than those before surgery,but there was no statistical significance between the two groups(P>0.05).There was nosignificant difference in pain recurrence rate,cyst recurrence rate and pregnancy success rate between OMA+DIE group and OMA group at1,3 and 5 years after surgery(P>0.05).Conclusion Laparoscopic ovarian cyst removal is beneficial to improve ovarian function,sexuallife quality,reduce pain,inhibit disease progression,and achieve a similar long-term prognosis in OMA patients or OMA pat

关 键 词：腹腔镜卵巢囊肿剔除术 卵巢子宫内膜异位囊肿 深部浸润型子宫内膜异位症 远期预后 

分 类 号：R713.6[医药卫生—妇产科学]