The latest research progress on the relationship between obstructive sleep apnea-hypopnea syndrome and metabolic syndrome  

作　　者：Tong Feng Qiong Ou 

机构地区：[1]Department of Respiratory and Critical Care Medicine,Sleep Center,Guangdong Provincial People's Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou,China

出　　处：《Sleep Research》2024年第1期5-12,共8页睡眠研究(英文)

基　　金：supported by the National Natural Science Foundation of China(grant no.82170098);remote interactive demonstration application of regional data of national health and basic physiological parameters(grant no.2022FY100803)to Qiong Ou.

摘　　要：Obstructive sleep apnea-hypopnea syndrome(OSAHS)is the most common subtype of sleep-disordered breathing,characterized by symptoms such as snoring,nocturnal sleep disturbances,and excessive daytime sleepiness.OSAHS is defined by recurrent upper airway collapses during sleep,leading to apneas or hypopneas.These episodes result in intermittent nocturnal hypoxia and sleep fragmentation,which provoke sympathetic activation,oxidative stress,and systemic inflammation,ultimately causing chronic damage across multiple bodily systems.OSAHS significantly increases the risk of various cardiovascular and metabolic disorders,including atherosclerosis,hyperten-sion,obesity,insulin resistance,and dyslipidemia.In China,approximately 176 million individuals are estimated to have OSAHS,with about 60 million experiencing moderate to severe forms of the condition.This paper reviews the epidemiological characteristics of OSAHS,the evolution of diagnostic criteria,and the association between OSAHS and metabolic syndrome(MetS),emphasizing the high prevalence of MetS among OSAHS patients.Through cross-sectional analysis,cohort studies,and interventional studies,the com-plex interactions between OSAHS and MetS are examined,proposing thera-peutic strategies to improve these metabolic anomalies,including continuous positive airway pressure therapy and weight management.

关 键 词：EPIDEMIOLOGY metabolic syndrome(MetS) obstructive sleep apnea-hypopnea syndrome(OSAHS) 

分 类 号：R76[医药卫生—耳鼻咽喉科]