Effects of partial sleep deprivation on arterial vasculature in university students  

作　　者：Vânia Freitas Clara Rocha Helder Santos 

机构地区：[1]Department of Clinical Physiology,Polytechnic Institute of Coimbra,Coimbra Health School,Coimbra,Portugal [2]Department of General Sciences,Polytechnic Institute of Coimbra,Coimbra Health School,Coimbra,Portugal [3]Department of Electrical and Computer Engineering,INESC Coimbra,University of Coimbra,Coimbra,Portugal

出　　处：《Sleep Research》2024年第1期27-35,共9页睡眠研究(英文)

基　　金：the Ethics Committee of the Polytechnic Institute of Coimbra(no.11 CEIPC/2019).

摘　　要：Objectives:Investigate whether partial sleep deprivation for five nights causes vascular changes in healthy university students.Study design:Prospective observational study.Methods:The study involved 18 young and healthy university students who were instructed to sleep as recommended for their age group for three consecutive nights.On the study's fourth night,participants slept a maximum of 5 h and,on the following nights,they slept less than 8 h.The assessments consisted of carotid assessment,flow-mediated dilation,and blood pressure(BP)monitoring.During the 8 days studied,participants used actigraphy in their daily routine.Results:A decrease in the BP of the common carotid artery(CCA),both systolic and diastolic resulted from partial sleep deprivation.After one night of partial sleep deprivation,there was a significant increase in peak systolic ve-locity and a significant decrease in the systolic diameter of CCA.However,the systolic velocity returned to values similar to those of the control group with the accumulation of nights with sleep deprivation.Conclusions:Our study indicates that those who do not get sufficient sleep,display sudden alterations in their cardiovascular parameters,which are consistent with an increased risk of developing coronary heart disease,myocardial infarction,stroke,and hypertension.

关 键 词：cardiovascular diseases endothelial dysfunction partial sleep deprivation vascular changes 

分 类 号：H31[语言文字—英语]