Metabolic regulation reduces the oxidative damage of arid lizards in response to moderate heat events  

作　　者：Xingzhi HAN Baojun SUN Qiong ZHANG LiweiTENG Fushun ZHANG Zhensheng LIU 

机构地区：[1]College of Wildlife and Protected Areas,Northeast Forestry University,Harbin,China [2]Key Laboratory of Animal Ecology and Conservation Biology,Institute of Zoology,Chinese Academy of Sciences,Beijing,China [3]Key Laboratory of Conservation Biology,National Forestry and Grassland Administration,Harbin,China [4]Grassland Research Institute,Chinese Academy of Agricultural Sciences,Hohhot,Inner Mongolia,China

出　　处：《Integrative Zoology》2024年第6期1034-1046,共13页整合动物学(英文版)

基　　金：This study was conducted in accordance with the guidelines and regulations set forth by the Animal Ethics Committee at the Institute of Zoology,Chinese Academy of Sciences(Approval No.IOZ-IACUC-2023-153).

摘　　要：Climate warming poses a significant threat to species worldwide,particularly those inhabiting arid and semi-arid regions where extreme temperatures are increasingly prevalent.However,empirical studies investigating how moderate heat events affect the physiological processes of arid and semi-arid animals are largely scarce.To address this knowledge gap,we used an arid and semi-arid lizard species(Phrynocephalus przewalskii)as a study system.We manipulated thermal environments to simulate moderate heat events(43.5±0.3°C during the heating period)for lizards and examined physiological and biochemical traits related to survival,metabolism,locomotion,oxidative stress,and telomere length.We found that the body condition and survival of the lizards were not significantly affected by moderate heat events,despite an increase in body temperature and a decrease in locomotion at high test temperatures were detected.Mechanistically,we found that the lizards exhibited down-regulated metabolic rates and enhanced activities of antioxidative enzymes,resulting in reduced oxidative damage and stable telomere length under moderate heat events.Based on these findings,which indicated a beneficial regulation of fitness by physiological and biochemical processes,we inferred that moderate heat events did not have a detrimental effect on the toad-headed agama,P.przewalskii.Overall,our research contributes to understanding the impacts of moderate heat events on arid and semi-arid species and highlights the adaptive responses and resilience exhibited by the toad-headed agama in the face of climate warming.

关 键 词：climate warming LIZARDS moderate heat events oxidative stress resting metabolic rate telomere length 

分 类 号：P31[天文地球—固体地球物理学]